FePt/GO 纳米复合材料制备方法及对胫骨骨折患者肢体功能的影响

Objective To investigate the method for the preparation of FePt/GO nanocomposite and to discuss its intervention effect on limb function of patients with tibial fracture. Methods FePt/GO nanocomposite was prepared by chemical reduction method, and its physical and chemical properties were evaluated from the aspects of thermal properties, moisture absorption resistance and mechanical properties. A total of 124 patients with tibial fracture were randomly divided into two groups, with 62 cases in each group. The patients in control group were treated with open reduction and internal fixation, while those in observation group were intervened with FePt/GO nanocomposite. The patients were followed-up for 6 months after operation, and the limb function and knee joint range of motion of two groups were compared. Results The wide peak of FePt/GO nanocomposite which occurred between 10° and 20°was the dispersion peak of FePt material, while the wide peak which occurred between 6° and 15°was the dispersion peak of GO material. The tensile property of FePt/GO nanocomposite was decreased with the increase of GO concentration; and the tensile strength of the nanocoposite with 10 phr PBA was decreased by 18% compared with that of pure samples (46.73 MPa). However, the bending property of the composite was increased with the increase of GO content. The scores of pain, function and activity, tibial plateau angle and posterior slope angle in observation group at 6 months after operation were higher than those in control group (P<0.05). Conclusion FePt/GO nanocomposite is successfully prepared by chemical reduction method, and the prepared material which has good physical and chemical properties can be used in patients with tibial fracture for improving limb function and joint range of motion, and serves as a novel material for the treatment of tibial fracture.