Expression of Dpp6 in mouse embryonic craniofacial development

Juan Du; Zhipeng Fan; Xin Ma; Yuanrong Gao; Yan Wu; Shuhong Liu; Yan Shen; Ming Fan; Songlin Wang

doi:10.1016/j.acthis.2010.08.001

Expression of Dpp6 in mouse embryonic craniofacial development

Juan Du
, Zhipeng Fan
, Xin Ma
, Yuanrong Gao
, Yan Wu
, Shuhong Liu
, Yan Shen
, Ming Fan
, Songlin Wang

Health Science Center

Capital Medical University
Institute of Basic Medical Sciences
Chinese Academy of Medical Sciences

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Dipeptidyl-peptidase-like protein 6 (DPP6), a member of the dipeptidyl aminopeptidase family, plays distinct roles in brain development, but its expression in embryonic craniofacial development is unknown. The expression pattern of Dpp6 in the maxillofacial region during mouse embryonic craniofacial development was analyzed by whole-mount in situ hybridization on sections and by real-time PCR analysis. Dpp6 expression was detected during mouse embryonic craniofacial development in embryos 11-13.5 days post-coitum (dpc). Real-time PCR showed high Dpp6 expression present in 11.5-13.5. dpc, and this then decreased as development of maxillofacial region progressed. The expression pattern of Dpp6 suggests that Dpp6 may be involved in embryonic craniofacial development.

Original language	English
Pages (from-to)	636-639
Number of pages	4
Journal	Acta Histochemica
Volume	113
Issue number	6
DOIs	https://doi.org/10.1016/j.acthis.2010.08.001
State	Published - Oct 2011

Keywords

Craniofacial development
Dpp6
Embryo
Mouse

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10.1016/j.acthis.2010.08.001

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title = "Expression of Dpp6 in mouse embryonic craniofacial development",

abstract = "Dipeptidyl-peptidase-like protein 6 (DPP6), a member of the dipeptidyl aminopeptidase family, plays distinct roles in brain development, but its expression in embryonic craniofacial development is unknown. The expression pattern of Dpp6 in the maxillofacial region during mouse embryonic craniofacial development was analyzed by whole-mount in situ hybridization on sections and by real-time PCR analysis. Dpp6 expression was detected during mouse embryonic craniofacial development in embryos 11-13.5 days post-coitum (dpc). Real-time PCR showed high Dpp6 expression present in 11.5-13.5. dpc, and this then decreased as development of maxillofacial region progressed. The expression pattern of Dpp6 suggests that Dpp6 may be involved in embryonic craniofacial development.",

keywords = "Craniofacial development, Dpp6, Embryo, Mouse",

author = "Juan Du and Zhipeng Fan and Xin Ma and Yuanrong Gao and Yan Wu and Shuhong Liu and Yan Shen and Ming Fan and Songlin Wang",

year = "2011",

month = oct,

doi = "10.1016/j.acthis.2010.08.001",

language = "英语",

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pages = "636--639",

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TY - JOUR

T1 - Expression of Dpp6 in mouse embryonic craniofacial development

AU - Du, Juan

AU - Fan, Zhipeng

AU - Ma, Xin

AU - Gao, Yuanrong

AU - Wu, Yan

AU - Liu, Shuhong

AU - Shen, Yan

AU - Fan, Ming

AU - Wang, Songlin

PY - 2011/10

Y1 - 2011/10

N2 - Dipeptidyl-peptidase-like protein 6 (DPP6), a member of the dipeptidyl aminopeptidase family, plays distinct roles in brain development, but its expression in embryonic craniofacial development is unknown. The expression pattern of Dpp6 in the maxillofacial region during mouse embryonic craniofacial development was analyzed by whole-mount in situ hybridization on sections and by real-time PCR analysis. Dpp6 expression was detected during mouse embryonic craniofacial development in embryos 11-13.5 days post-coitum (dpc). Real-time PCR showed high Dpp6 expression present in 11.5-13.5. dpc, and this then decreased as development of maxillofacial region progressed. The expression pattern of Dpp6 suggests that Dpp6 may be involved in embryonic craniofacial development.

AB - Dipeptidyl-peptidase-like protein 6 (DPP6), a member of the dipeptidyl aminopeptidase family, plays distinct roles in brain development, but its expression in embryonic craniofacial development is unknown. The expression pattern of Dpp6 in the maxillofacial region during mouse embryonic craniofacial development was analyzed by whole-mount in situ hybridization on sections and by real-time PCR analysis. Dpp6 expression was detected during mouse embryonic craniofacial development in embryos 11-13.5 days post-coitum (dpc). Real-time PCR showed high Dpp6 expression present in 11.5-13.5. dpc, and this then decreased as development of maxillofacial region progressed. The expression pattern of Dpp6 suggests that Dpp6 may be involved in embryonic craniofacial development.

KW - Craniofacial development

KW - Dpp6

KW - Embryo

KW - Mouse

UR - https://www.scopus.com/pages/publications/79957891329

U2 - 10.1016/j.acthis.2010.08.001

DO - 10.1016/j.acthis.2010.08.001

M3 - 文章

C2 - 20817268

AN - SCOPUS:79957891329

SN - 0065-1281

VL - 113

SP - 636

EP - 639

JO - Acta Histochemica

JF - Acta Histochemica

IS - 6

ER -

Expression of Dpp6 in mouse embryonic craniofacial development

Abstract

Keywords

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