Evaluation of the anticancer effects induced by cold atmospheric plasma on leukemia stem cells

Rui Feng; Ning Ning; Miao Tian; Sansan Peng; Shuai Wang; Bing Li; Hao Zhang; Dehui Xu

doi:10.1088/2516-1067/ab9154

Evaluation of the anticancer effects induced by cold atmospheric plasma on leukemia stem cells

Rui Feng
, Ning Ning
, Miao Tian
, Sansan Peng
, Shuai Wang
, Bing Li
, Hao Zhang
, Dehui Xu

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The application of cold atmospheric plasma (CAP) in cancer treatment has received extensive attention. However, little research was observed on the anticancer effects of CAP to tumor stem cells. Here, we analyzed the discharge characteristics of a CAP jet and plasma-induced effects on acute myeloid leukemia (AML) stem cells. Our results showed that the most active particles can be produced when helium is doped with 0.5% oxygen and the jet device is driven by a pulsed power supply. And when using this plasma jet device to treat acute myeloid leukemia (AML) stem cells, it is found that CAP jet can effectively inhibit the cell activity of AML stem cells, which provides new ideas for the treatment of AML.

Original language	English
Article number	024001
Journal	Plasma Research Express
Volume	2
Issue number	2
DOIs	https://doi.org/10.1088/2516-1067/ab9154
State	Published - 19 Jun 2020

Keywords

Absorption spectrum
Acute myeloid leukemia stem cells
Liquid active particles
Plasma jet

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1088/2516-1067/ab9154

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title = "Evaluation of the anticancer effects induced by cold atmospheric plasma on leukemia stem cells",

abstract = "The application of cold atmospheric plasma (CAP) in cancer treatment has received extensive attention. However, little research was observed on the anticancer effects of CAP to tumor stem cells. Here, we analyzed the discharge characteristics of a CAP jet and plasma-induced effects on acute myeloid leukemia (AML) stem cells. Our results showed that the most active particles can be produced when helium is doped with 0.5\% oxygen and the jet device is driven by a pulsed power supply. And when using this plasma jet device to treat acute myeloid leukemia (AML) stem cells, it is found that CAP jet can effectively inhibit the cell activity of AML stem cells, which provides new ideas for the treatment of AML.",

keywords = "Absorption spectrum, Acute myeloid leukemia stem cells, Liquid active particles, Plasma jet",

author = "Rui Feng and Ning Ning and Miao Tian and Sansan Peng and Shuai Wang and Bing Li and Hao Zhang and Dehui Xu",

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TY - JOUR

T1 - Evaluation of the anticancer effects induced by cold atmospheric plasma on leukemia stem cells

AU - Feng, Rui

AU - Ning, Ning

AU - Tian, Miao

AU - Peng, Sansan

AU - Wang, Shuai

AU - Li, Bing

AU - Zhang, Hao

AU - Xu, Dehui

PY - 2020/6/19

Y1 - 2020/6/19

N2 - The application of cold atmospheric plasma (CAP) in cancer treatment has received extensive attention. However, little research was observed on the anticancer effects of CAP to tumor stem cells. Here, we analyzed the discharge characteristics of a CAP jet and plasma-induced effects on acute myeloid leukemia (AML) stem cells. Our results showed that the most active particles can be produced when helium is doped with 0.5% oxygen and the jet device is driven by a pulsed power supply. And when using this plasma jet device to treat acute myeloid leukemia (AML) stem cells, it is found that CAP jet can effectively inhibit the cell activity of AML stem cells, which provides new ideas for the treatment of AML.

AB - The application of cold atmospheric plasma (CAP) in cancer treatment has received extensive attention. However, little research was observed on the anticancer effects of CAP to tumor stem cells. Here, we analyzed the discharge characteristics of a CAP jet and plasma-induced effects on acute myeloid leukemia (AML) stem cells. Our results showed that the most active particles can be produced when helium is doped with 0.5% oxygen and the jet device is driven by a pulsed power supply. And when using this plasma jet device to treat acute myeloid leukemia (AML) stem cells, it is found that CAP jet can effectively inhibit the cell activity of AML stem cells, which provides new ideas for the treatment of AML.

KW - Absorption spectrum

KW - Acute myeloid leukemia stem cells

KW - Liquid active particles

KW - Plasma jet

UR - https://www.scopus.com/pages/publications/85092613091

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DO - 10.1088/2516-1067/ab9154

M3 - 文章

AN - SCOPUS:85092613091

SN - 2516-1067

VL - 2

JO - Plasma Research Express

JF - Plasma Research Express

IS - 2

M1 - 024001

ER -

Evaluation of the anticancer effects induced by cold atmospheric plasma on leukemia stem cells

Abstract

Keywords

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