Estimation of postmortem interval using FTIR spectroscopy in rats' cardiac muscle

Ping Huang; Chang Pei Su; Shi Song Li; Bo Xing; Ya Tuo; Qing Yang Lu; Yong Ke; Zhen Yuan Wang

doi:10.3969/j.issn.1004-5619.2010.01.001

Estimation of postmortem interval using FTIR spectroscopy in rats' cardiac muscle

Ping Huang
, Chang Pei Su
, Shi Song Li
, Bo Xing
, Ya Tuo
, Qing Yang Lu
, Yong Ke
, Zhen Yuan Wang

Health Science Center

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Objective: FTIR(Fourier transform infrared) spectroscopy was applied to observe the process of postmortem degradation in rats' cardiac muscle and provided a new method for the estimation of postmortem interval(PMI). Methods: The rats were sacrificed by cervical dislocation and the bodies were kept in a controlled environmental chamber set at (20±2)°C. The FTIR spectra was applied to measure the changes of different chemical group from rats' left ventricle muscle at the different time point postmortem. Results: There were not obvious changes for the main FTIR absorbance peaks. But the different FTIR absorbance at the wave-number(cm^-1) indicated the three types: increase, decrease, stable. The various absorbance ratios also demonstrated the similar changes. Conclusion: FTIR spectroscopy may be potentially used as an effective method for estimating PMI in forensic practice using cardiac muscle tissue.

Original language	English
Pages (from-to)	1-5
Number of pages	5
Journal	Journal of Forensic Medicine
Volume	26
Issue number	1
DOIs	https://doi.org/10.3969/j.issn.1004-5619.2010.01.001
State	Published - Feb 2010

Keywords

Estimation of postmortem interval
Forensic pathology
Myocardium
Rats
Spectroscopy, Fourier transform infrared

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10.3969/j.issn.1004-5619.2010.01.001

Cite this

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title = "Estimation of postmortem interval using FTIR spectroscopy in rats' cardiac muscle",

abstract = "Objective: FTIR(Fourier transform infrared) spectroscopy was applied to observe the process of postmortem degradation in rats' cardiac muscle and provided a new method for the estimation of postmortem interval(PMI). Methods: The rats were sacrificed by cervical dislocation and the bodies were kept in a controlled environmental chamber set at (20±2)°C. The FTIR spectra was applied to measure the changes of different chemical group from rats' left ventricle muscle at the different time point postmortem. Results: There were not obvious changes for the main FTIR absorbance peaks. But the different FTIR absorbance at the wave-number(cm-1) indicated the three types: increase, decrease, stable. The various absorbance ratios also demonstrated the similar changes. Conclusion: FTIR spectroscopy may be potentially used as an effective method for estimating PMI in forensic practice using cardiac muscle tissue.",

keywords = "Estimation of postmortem interval, Forensic pathology, Myocardium, Rats, Spectroscopy, Fourier transform infrared",

author = "Ping Huang and Su, \{Chang Pei\} and Li, \{Shi Song\} and Bo Xing and Ya Tuo and Lu, \{Qing Yang\} and Yong Ke and Wang, \{Zhen Yuan\}",

year = "2010",

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doi = "10.3969/j.issn.1004-5619.2010.01.001",

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T1 - Estimation of postmortem interval using FTIR spectroscopy in rats' cardiac muscle

AU - Huang, Ping

AU - Su, Chang Pei

AU - Li, Shi Song

AU - Xing, Bo

AU - Tuo, Ya

AU - Lu, Qing Yang

AU - Ke, Yong

AU - Wang, Zhen Yuan

PY - 2010/2

Y1 - 2010/2

N2 - Objective: FTIR(Fourier transform infrared) spectroscopy was applied to observe the process of postmortem degradation in rats' cardiac muscle and provided a new method for the estimation of postmortem interval(PMI). Methods: The rats were sacrificed by cervical dislocation and the bodies were kept in a controlled environmental chamber set at (20±2)°C. The FTIR spectra was applied to measure the changes of different chemical group from rats' left ventricle muscle at the different time point postmortem. Results: There were not obvious changes for the main FTIR absorbance peaks. But the different FTIR absorbance at the wave-number(cm-1) indicated the three types: increase, decrease, stable. The various absorbance ratios also demonstrated the similar changes. Conclusion: FTIR spectroscopy may be potentially used as an effective method for estimating PMI in forensic practice using cardiac muscle tissue.

AB - Objective: FTIR(Fourier transform infrared) spectroscopy was applied to observe the process of postmortem degradation in rats' cardiac muscle and provided a new method for the estimation of postmortem interval(PMI). Methods: The rats were sacrificed by cervical dislocation and the bodies were kept in a controlled environmental chamber set at (20±2)°C. The FTIR spectra was applied to measure the changes of different chemical group from rats' left ventricle muscle at the different time point postmortem. Results: There were not obvious changes for the main FTIR absorbance peaks. But the different FTIR absorbance at the wave-number(cm-1) indicated the three types: increase, decrease, stable. The various absorbance ratios also demonstrated the similar changes. Conclusion: FTIR spectroscopy may be potentially used as an effective method for estimating PMI in forensic practice using cardiac muscle tissue.

KW - Estimation of postmortem interval

KW - Forensic pathology

KW - Myocardium

KW - Rats

KW - Spectroscopy, Fourier transform infrared

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Estimation of postmortem interval using FTIR spectroscopy in rats' cardiac muscle

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Keywords

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