Electroreductive Cross-Electrophile Coupling (eXEC) Reactions

Electrochemistry utilizes electrons as a potent, controllable, and traceless alternative to chemical oxidants or reductants, and typically offers a more sustainable option for achieving selective organic synthesis. Recently, the merger of electrochemistry with readily available electrophiles has been recognized as a viable and increasingly popular methodology for efficiently constructing challenging C−C and C-heteroatom bonds in a sustainable manner for complex organic molecules. In this mini-review, we have systematically summarized the most recent advances in electroreductive cross-electrophile coupling (eXEC) reactions during the last decade. Our focus has been on readily available electrophiles, including aryl and alkyl organic (pseudo)halides, as well as small molecules such as CO₂, SO₂, and D₂O.