Abstract
Objective: To analyze the relationship between the distribution frequency of matching human leukocyte antigen (HLA) locus and the long-term survival of recipients after kidney transplantation.
Methods: The HLA locus of kidney transplantation patients was analyzed by HLA serologic classification method. The distribution frequency of matching HLA locus of recipients which survived more than 10 years was compared with that of recipients which survived less than 10 years.
Results: For HLA matching locus of 490 recipients who had lived more than 10 years, HLA A2, B5, B35 and DR9 had significantly higher frequencies than those of 259 recipients who survived less than 10 years. On the other hand, HLA B13 and B46 had a significantly lower frequency than that of recipients who survived less than 10 years (P<0.05).
Conclusion: HLA A2, B5, B35 and DR9 matching may be conducive to the long-term survival of recipients after kidney transplantation.
| Original language | English |
|---|---|
| Pages (from-to) | 513-517 |
| Number of pages | 5 |
| Journal | Journal of Xi'an Jiaotong University (Medical Sciences) |
| Volume | 35 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1 Jul 2014 |
Keywords
- Human leukocyte antigen (HLA) matching
- Kidney transplantation
- Survival rate