Development of a fluorescent probe for detecting Al³⁺ in cooked wheaten food based on phosphonic acid group functionalized polythiophene derivatives

As an unnecessary trace element, the content of aluminium in biological systems should be strictly controlled. Therefore, it was necessary to develop a convenient method for detection of aluminium ions. In this study, a fluorescent probe based on polythiophene derivatives was developed and used to detect Al³⁺ in Chinese traditional pasta. The fluorescence of this probe showed a significant decrease in hexamethylenetetramine–HCl buffer solution (pH 5) when Al³⁺ was present. In addition, the probe exhibited good sensitivity and selectivity to Al³⁺ over other metal ions when EDTA was used as the masking agent. Fluorescence intensity had a good linear relationship with the Al³⁺ concentration in the range 0.1–10 μM and the limit of detection for Al³⁺ was 39 nM. Furthermore, the probe was successfully applied to detect Al³⁺ in food samples and the results were consistent with ICP–AES.