TY - GEN
T1 - Detection of stress hormones by a microfluidic-integrated polycarbazole/fullerene photodetector
AU - Pires, Nuno M.M.
AU - Dong, Tao
PY - 2013
Y1 - 2013
N2 - A novel photodetector integrated microfluidic system for chemiluminescence (CL) detection is reported. The system incorporates a polycarbazole/fullerene photodiode whose optical characteristics (i.e. dark current, external quantum efficiency and photosensitivity) are described here. Using a CL immunoassay for detecting the stress hormone cortisol, the integrated photodetector achieved a detection sensitivity of 1.775 pA × nM-1 and a detection limit of less than 0.28 nM. The device would be a powerful low-cost alternative to silicon photodiode and photomultiplier tube for bioanalytical assays, with potentially wide-ranging applications within point-of-care diagnostics.
AB - A novel photodetector integrated microfluidic system for chemiluminescence (CL) detection is reported. The system incorporates a polycarbazole/fullerene photodiode whose optical characteristics (i.e. dark current, external quantum efficiency and photosensitivity) are described here. Using a CL immunoassay for detecting the stress hormone cortisol, the integrated photodetector achieved a detection sensitivity of 1.775 pA × nM-1 and a detection limit of less than 0.28 nM. The device would be a powerful low-cost alternative to silicon photodiode and photomultiplier tube for bioanalytical assays, with potentially wide-ranging applications within point-of-care diagnostics.
UR - https://www.scopus.com/pages/publications/84886575186
U2 - 10.1109/EMBC.2013.6610539
DO - 10.1109/EMBC.2013.6610539
M3 - 会议稿件
C2 - 24110726
AN - SCOPUS:84886575186
SN - 9781457702167
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 4470
EP - 4473
BT - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
T2 - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Y2 - 3 July 2013 through 7 July 2013
ER -