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Design and characterization of a multiplexed capillary-driven lab-on-chip for water quality analysis

  • Carlos Honrado
  • , Carlos A. Silva
  • , Tao Dong
  • University of Minho
  • Faculty of Engineering and Marine Sciences

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

The concept of a novel point-of-care (POC) microfluidic device for water-quality analysis was presented. The device employs capillary phenomena as filling process and its design is compatible to the use of organic photodiodes for bio-sensing. Three different device conformations were described and characterized. The series model attained a small total filling time (TFT) of around 2.80s. However, as disadvantage, this conformation cannot be used in bio-chemiluminescence (BCL) reactions having multiple analytes in common. For the parallel model, a high TFT of around 86s was obtained and some advancing/receding of fluid during the filling process was observed. This could lead to weaker optical signals and higher noise in the sensing area. Regarding the parallel-series, a TFT value of 35s was attained. This is a compromise between previously studied conformations. Also, no advancing/receding of fluid has occurred and a more compact design was created, as desired for POC applications.

Original languageEnglish
Title of host publicationIEEE MeMeA 2014 - IEEE International Symposium on Medical Measurements and Applications, Proceedings
PublisherIEEE Computer Society
ISBN (Print)9781479929207
DOIs
StatePublished - 2014
Externally publishedYes
Event9th IEEE International Symposium on Medical Measurements and Applications, IEEE MeMeA 2014 - Lisbon, Portugal
Duration: 11 Jun 201412 Jun 2014

Publication series

NameIEEE MeMeA 2014 - IEEE International Symposium on Medical Measurements and Applications, Proceedings

Conference

Conference9th IEEE International Symposium on Medical Measurements and Applications, IEEE MeMeA 2014
Country/TerritoryPortugal
CityLisbon
Period11/06/1412/06/14

Keywords

  • Bio-chemiluminescence
  • Capillary phenomena
  • Microfluidics
  • Point-of-care
  • Polymer photodiode
  • Water quality analysis

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