Deconstruction as a strategy for the design of libraries of self-assembling dendrons

Bringing down the dendron: The deconstruction of self-assembling dendrons represents a new strategy for the rational design of libraries of self-assembling dendrons with unprecedented primary structure (see picture). In this strategy, molecular targets are designed by systematically removing branches from a parent dendron. This approach provides a diversity of molecular topologies unencountered in the generational synthesis of dendrons.