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Corrigendum to “Promethazine inhibits proliferation and promotes apoptosis in colorectal cancer cells by suppressing the PI3K/AKT pathway” [Biomed. Pharmacotherapy 143(2021)112174](S0753332221009586)(10.1016/j.biopha.2021.112174)

  • Xinyue Tan
  • , Liuyun Gong
  • , Xinyue Li
  • , Xinyue Zhang
  • , Jiahao Sun
  • , Xuehui Luo
  • , Qi Wang
  • , Jie Chen
  • , Lina Xie
  • , Suxia Han
  • Xi'an Jiaotong University

Research output: Contribution to journalComment/debate

Abstract

The authors regret the incorrect publication of Fig.4 and the incorrect SW480 cell line name in the original article. The correct Fig.4 is presented below:[Formula presented] The corrected cell line name is presented below: 3 Results 3.4 PMTZ induces the apoptosis of CRC cells by altering the expression of Bcl-2, Bax, and caspase-3 To explore whether PMTZ can induce the apoptosis of HT29 and SW480 cells, Annexin/PE and 7AAD staining were performed for flow cytometry analysis. The concentration of PMTZ was positively correlated with the degree of apoptosis (Figure 4). After being treated with 20 µmol/L PMTZ for 24 h, the apoptosis rates of the HT29 and SW480 cells were 32.3 % and 36.3 %, respectively, which were approximately 3.8–3.9 times higher than that of the control cells; after treatment with 40 µmol/L PMTZ for 24 h, the apoptosis rates of the HT29 and SW480 cells were 50.1 % and 40.4 %, approximately 4.6–6 times higher than that of the control cells. In summary, PMTZ may induce apoptosis in HT29 and SW480 CRC cells. The authors would like to apologise for any inconvenience caused. DOI of original article: 10.1016/j.biopha.2021.112174

Original languageEnglish
Article number116913
JournalBiomedicine and Pharmacotherapy
Volume176
DOIs
StatePublished - Jul 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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