Correlation between single point pulse wave velocity and coronary artery stenosis quantity

Objective: To study the correlation between single point pulse wave velocity (PWVβ) of different peripheral arteries and coronary artery stenosis quantity obtained by coronary arteriongraphy so as to explore the diagnostic value of PWVβ in coronary heart disease. Methods: We made a retrospective analysis of 183 patients receiving coronary arteriongraphy in our hospital from October 2013 to May 2014.Based on stenosis quantity of coronary artery, the patients were divided into one-vessel lesion group, double-vessel lesion group, multi-vessel lesion group, and nonstenosis as control group. Clinical data of all the patients were collected before coronary arteriongraphy. Different peripheral artery PWVβ was measured with vascular echo tracking (ET) technology for statistical analysis. Results: As the lesion vessel number increased, PWVβ and β values in three peripheral arteries presented a rising tendency. Correlation analysis indicated that PWVβ values in the three peripheral arteries showed a positive correlation with coronary artery involvement degree. The correlation between PWVβ value of the common carotid artery and coronary artery involvement degree was most obvious, followed by the femoral artery and the popliteal artery. The sensitivity, specificity, positive predictive value, negative predictive value and Youden index of the common carotid artery PWVβ value to diagnose coronary heart disease were 91.2%, 84.5%, 92.7%, 81.7 and 0.76, respectively. Non-conditional multi-factor Logistic regression analysis was implemented by choosing age, sex, smoking history, hypertension history, diabetes history, hyperlipemia, BMI, HDL-C, LDL-C, TC, TG, GLU, SBP, DBP, UA, Cr, and PWVβ value as independent variables, and the degree of coronary artery disease as dependent variable. The results revealed that age, hypertension history, diabetes history, and PWVβ value were independent risk factors for coronary heart disease. Conclusion: PWVβ value can be regarded as one index for observing artherosclerosis lesion degree and predicting early lesion. PWVβ value of the common carotid artery can be an important index for dynamically observing the occurrence and development of artherosclerosis.