Copper-catalyzed tandem oxidative cyclization of cinnamamides with benzyl hydrocarbons through cross-dehydrogenative coupling

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Abstract

The copper-catalyzed tandem oxidative cyclization of cinnamamides with benzyl hydrocarbons through the direct cross-dehydrogenative coupling of sp3 and sp2 C–H bonds has been developed. Satisfactorily, ethers, alcohols and alkanes could also be used instead of benzyl hydrocarbons in this transformation, which allows rapid access to diverse dihydroquinolinones in one step.

Original languageEnglish
Pages (from-to)3589-3591
Number of pages3
JournalChemical Communications
Volume50
Issue number27
DOIs
StatePublished - 6 Mar 2014

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