Copper-catalyzed oxidative ipso-annulation of activated alkynes with silanes: An approach to 3-silyl azaspiro[4,5]trienones

Pin Gao; Wanwan Zhang; Zhicheng Zhang

doi:10.1021/acs.orglett.6b02781

Copper-catalyzed oxidative ipso-annulation of activated alkynes with silanes: An approach to 3-silyl azaspiro[4,5]trienones

Pin Gao
, Wanwan Zhang
, Zhicheng Zhang

School of Chemistry

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Abstract

A novel strategy of silylation and dearomatization of activated alkynes with silanes to synthesize azaspiro[4,5]trienones is developed, which could be facilely achieved through a tandem difunctionalization of alkyne, dearomatization, and oxidation and provided a facile approach to produce useful 3-silyl azaspiro[4,5]trienones in an efficient manner.

Original language	English
Pages (from-to)	5820-5823
Number of pages	4
Journal	Organic Letters
Volume	18
Issue number	22
DOIs	https://doi.org/10.1021/acs.orglett.6b02781
State	Published - 18 Nov 2016

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abstract = "A novel strategy of silylation and dearomatization of activated alkynes with silanes to synthesize azaspiro[4,5]trienones is developed, which could be facilely achieved through a tandem difunctionalization of alkyne, dearomatization, and oxidation and provided a facile approach to produce useful 3-silyl azaspiro[4,5]trienones in an efficient manner.",

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AU - Zhang, Wanwan

AU - Zhang, Zhicheng

PY - 2016/11/18

Y1 - 2016/11/18

N2 - A novel strategy of silylation and dearomatization of activated alkynes with silanes to synthesize azaspiro[4,5]trienones is developed, which could be facilely achieved through a tandem difunctionalization of alkyne, dearomatization, and oxidation and provided a facile approach to produce useful 3-silyl azaspiro[4,5]trienones in an efficient manner.

AB - A novel strategy of silylation and dearomatization of activated alkynes with silanes to synthesize azaspiro[4,5]trienones is developed, which could be facilely achieved through a tandem difunctionalization of alkyne, dearomatization, and oxidation and provided a facile approach to produce useful 3-silyl azaspiro[4,5]trienones in an efficient manner.

UR - https://www.scopus.com/pages/publications/84996956035

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DO - 10.1021/acs.orglett.6b02781

M3 - 文章

AN - SCOPUS:84996956035

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IS - 22

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Copper-catalyzed oxidative ipso-annulation of activated alkynes with silanes: An approach to 3-silyl azaspiro[4,5]trienones

Abstract

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