Contrast-enhanced sonography of thyroid nodules

Jue Jiang; Lili Huang; Hongli Zhang; Wenqi Ma; Xue Shang; Qi Zhou; Ya Gao; Shanshan Yu; Yanhua Qi

doi:10.1002/jcu.22240

Contrast-enhanced sonography of thyroid nodules

Jue Jiang
, Lili Huang
, Hongli Zhang
, Wenqi Ma
, Xue Shang
, Qi Zhou
, Ya Gao
, Shanshan Yu
, Yanhua Qi

Health Science Center

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Purpose: To investigate the value of contrast-enhanced ultrasound (CEUS) in the differentiation of benign and malignant nodules. Methods: One hundred eighty-nine patients with 213 thyroid nodules were enrolled in this retrospective study. All patients underwent preoperative CEUS and were subsequently scheduled for surgery. The pathology results were obtained after surgery. The time-intensity curves were plotted with TomTec software. The quantitative parameters of the time-intensity curve, such as the maximum intensity of peak (IMAX), the rise time from 10% to 90% of the IMAX, and the time to peak, were compared between the benign and malignant nodules. Results: There were no significant differences in the rise time or the time to peak among thyroid papillary carcinoma, nodular goiter, and follicular adenoma. However, a significant difference was identified in the IMAX. Conclusions: A quantitative evaluation of CEUS is helpful to differentiate benign and malignant thyroid nodules.

Original language	English
Pages (from-to)	153-156
Number of pages	4
Journal	Journal of Clinical Ultrasound
Volume	43
Issue number	3
DOIs	https://doi.org/10.1002/jcu.22240
State	Published - 1 Mar 2015

Keywords

Cancer
Contrast agents
Follicular adenoma
Goiter
Quantitative parameter
Thyroid
Time-intensity curve
Ultrasonography

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/jcu.22240

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@article{59071fe0575f4454ba28b711ba43f9f5,

title = "Contrast-enhanced sonography of thyroid nodules",

abstract = "Purpose: To investigate the value of contrast-enhanced ultrasound (CEUS) in the differentiation of benign and malignant nodules. Methods: One hundred eighty-nine patients with 213 thyroid nodules were enrolled in this retrospective study. All patients underwent preoperative CEUS and were subsequently scheduled for surgery. The pathology results were obtained after surgery. The time-intensity curves were plotted with TomTec software. The quantitative parameters of the time-intensity curve, such as the maximum intensity of peak (IMAX), the rise time from 10\% to 90\% of the IMAX, and the time to peak, were compared between the benign and malignant nodules. Results: There were no significant differences in the rise time or the time to peak among thyroid papillary carcinoma, nodular goiter, and follicular adenoma. However, a significant difference was identified in the IMAX. Conclusions: A quantitative evaluation of CEUS is helpful to differentiate benign and malignant thyroid nodules.",

keywords = "Cancer, Contrast agents, Follicular adenoma, Goiter, Quantitative parameter, Thyroid, Time-intensity curve, Ultrasonography",

author = "Jue Jiang and Lili Huang and Hongli Zhang and Wenqi Ma and Xue Shang and Qi Zhou and Ya Gao and Shanshan Yu and Yanhua Qi",

note = "Publisher Copyright: {\textcopyright} 2014 Wiley Periodicals, Inc.",

year = "2015",

month = mar,

day = "1",

doi = "10.1002/jcu.22240",

language = "英语",

volume = "43",

pages = "153--156",

journal = "Journal of Clinical Ultrasound",

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TY - JOUR

T1 - Contrast-enhanced sonography of thyroid nodules

AU - Jiang, Jue

AU - Huang, Lili

AU - Zhang, Hongli

AU - Ma, Wenqi

AU - Shang, Xue

AU - Zhou, Qi

AU - Gao, Ya

AU - Yu, Shanshan

AU - Qi, Yanhua

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Purpose: To investigate the value of contrast-enhanced ultrasound (CEUS) in the differentiation of benign and malignant nodules. Methods: One hundred eighty-nine patients with 213 thyroid nodules were enrolled in this retrospective study. All patients underwent preoperative CEUS and were subsequently scheduled for surgery. The pathology results were obtained after surgery. The time-intensity curves were plotted with TomTec software. The quantitative parameters of the time-intensity curve, such as the maximum intensity of peak (IMAX), the rise time from 10% to 90% of the IMAX, and the time to peak, were compared between the benign and malignant nodules. Results: There were no significant differences in the rise time or the time to peak among thyroid papillary carcinoma, nodular goiter, and follicular adenoma. However, a significant difference was identified in the IMAX. Conclusions: A quantitative evaluation of CEUS is helpful to differentiate benign and malignant thyroid nodules.

AB - Purpose: To investigate the value of contrast-enhanced ultrasound (CEUS) in the differentiation of benign and malignant nodules. Methods: One hundred eighty-nine patients with 213 thyroid nodules were enrolled in this retrospective study. All patients underwent preoperative CEUS and were subsequently scheduled for surgery. The pathology results were obtained after surgery. The time-intensity curves were plotted with TomTec software. The quantitative parameters of the time-intensity curve, such as the maximum intensity of peak (IMAX), the rise time from 10% to 90% of the IMAX, and the time to peak, were compared between the benign and malignant nodules. Results: There were no significant differences in the rise time or the time to peak among thyroid papillary carcinoma, nodular goiter, and follicular adenoma. However, a significant difference was identified in the IMAX. Conclusions: A quantitative evaluation of CEUS is helpful to differentiate benign and malignant thyroid nodules.

KW - Cancer

KW - Contrast agents

KW - Follicular adenoma

KW - Goiter

KW - Quantitative parameter

KW - Thyroid

KW - Time-intensity curve

KW - Ultrasonography

UR - https://www.scopus.com/pages/publications/84924247929

U2 - 10.1002/jcu.22240

DO - 10.1002/jcu.22240

M3 - 文章

C2 - 25328134

AN - SCOPUS:84924247929

SN - 0091-2751

VL - 43

SP - 153

EP - 156

JO - Journal of Clinical Ultrasound

JF - Journal of Clinical Ultrasound

IS - 3

ER -

Contrast-enhanced sonography of thyroid nodules

Abstract

Keywords

UN SDGs

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