Chemiluminescent organic nanophotosensitizer for a penetration depth independent photodynamic therapy

Xiaomei Lu; Xingwen Song; Qi Wang; Wenbo Hu; Wei Shi; Yufu Tang; Zizi Wu; Quli Fan; Wei Huang

doi:10.1039/d0ra01477j

Chemiluminescent organic nanophotosensitizer for a penetration depth independent photodynamic therapy

Xiaomei Lu
, Xingwen Song
, Qi Wang
, Wenbo Hu
, Wei Shi
, Yufu Tang
, Zizi Wu
, Quli Fan
, Wei Huang

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Photodynamic therapy initiated by external photoexcitation is a clinically-approved therapeutic paradigm, but its practical application has been severely hindered by the shallow penetration of light. Here, we describe a penetration-independent PDT modality using a chemiluminescent organic nanophotosensitizer, which is activated by hydrogen peroxide instead of external photoexcitation.

Original language	English
Pages (from-to)	11861-11864
Number of pages	4
Journal	RSC Advances
Volume	10
Issue number	20
DOIs	https://doi.org/10.1039/d0ra01477j
State	Published - 24 Mar 2020
Externally published	Yes

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10.1039/d0ra01477j

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title = "Chemiluminescent organic nanophotosensitizer for a penetration depth independent photodynamic therapy",

abstract = "Photodynamic therapy initiated by external photoexcitation is a clinically-approved therapeutic paradigm, but its practical application has been severely hindered by the shallow penetration of light. Here, we describe a penetration-independent PDT modality using a chemiluminescent organic nanophotosensitizer, which is activated by hydrogen peroxide instead of external photoexcitation.",

author = "Xiaomei Lu and Xingwen Song and Qi Wang and Wenbo Hu and Wei Shi and Yufu Tang and Zizi Wu and Quli Fan and Wei Huang",

note = "Publisher Copyright: This journal is {\textcopyright} The Royal Society of Chemistry.",

year = "2020",

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T1 - Chemiluminescent organic nanophotosensitizer for a penetration depth independent photodynamic therapy

AU - Lu, Xiaomei

AU - Song, Xingwen

AU - Wang, Qi

AU - Hu, Wenbo

AU - Shi, Wei

AU - Tang, Yufu

AU - Wu, Zizi

AU - Fan, Quli

AU - Huang, Wei

PY - 2020/3/24

Y1 - 2020/3/24

N2 - Photodynamic therapy initiated by external photoexcitation is a clinically-approved therapeutic paradigm, but its practical application has been severely hindered by the shallow penetration of light. Here, we describe a penetration-independent PDT modality using a chemiluminescent organic nanophotosensitizer, which is activated by hydrogen peroxide instead of external photoexcitation.

AB - Photodynamic therapy initiated by external photoexcitation is a clinically-approved therapeutic paradigm, but its practical application has been severely hindered by the shallow penetration of light. Here, we describe a penetration-independent PDT modality using a chemiluminescent organic nanophotosensitizer, which is activated by hydrogen peroxide instead of external photoexcitation.

UR - https://www.scopus.com/pages/publications/85082777698

U2 - 10.1039/d0ra01477j

DO - 10.1039/d0ra01477j

M3 - 文章

AN - SCOPUS:85082777698

SN - 2046-2069

VL - 10

SP - 11861

EP - 11864

JO - RSC Advances

JF - RSC Advances

IS - 20

ER -

Chemiluminescent organic nanophotosensitizer for a penetration depth independent photodynamic therapy

Abstract

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