Chemiluminescence determination of fluoroquinolone antibiotics using a soluble manganese (IV)-sulphite system

Jianxiu Du; Yinhuan Li; Jiuru Lu

doi:10.1002/bio.798

Chemiluminescence determination of fluoroquinolone antibiotics using a soluble manganese (IV)-sulphite system

Jianxiu Du
, Yinhuan Li
, Jiuru Lu

School of Chemistry

Shaanxi Normal University

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

The reaction of soluble manganese (IV) with sulphite in acidic condition was found to elicit weak chemiluminescence (CL). The CL signal was remarkably enhanced in the presence of three fluoroquinolones, viz. norfloxacin, ofloxacin and ciprofloxacin. Based on these observations, a new flow-injection CL method was developed for the determination of these fluoroquinolones. The method allows determination in the range 5.0 × 10^-8-1.0 × 10 ^-6 mol/L for norfloxacin, 1.0 × 10^-7-8.0 × 10^-6 mol/ L for ofloxacin and 1.0 × 10-7-3.0 × 10 ^-5 mol/L for ciprofloxacin, with detection limits of 3 × 10^-8 mol/L, 5 × 10^-8 mol/L and 3 × 10 ^-8 mol/L, respectively. The method was applied to the determination of fluoroquinolones in pharmaceutical preparations.

Original language	English
Pages (from-to)	30-35
Number of pages	6
Journal	Luminescence
Volume	20
Issue number	1
DOIs	https://doi.org/10.1002/bio.798
State	Published - 2005

Keywords

Chemiluminescence
Flow injection
Fluoroquinolones
Soluble manganese (IV)

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10.1002/bio.798

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title = "Chemiluminescence determination of fluoroquinolone antibiotics using a soluble manganese (IV)-sulphite system",

abstract = "The reaction of soluble manganese (IV) with sulphite in acidic condition was found to elicit weak chemiluminescence (CL). The CL signal was remarkably enhanced in the presence of three fluoroquinolones, viz. norfloxacin, ofloxacin and ciprofloxacin. Based on these observations, a new flow-injection CL method was developed for the determination of these fluoroquinolones. The method allows determination in the range 5.0 × 10-8-1.0 × 10 -6 mol/L for norfloxacin, 1.0 × 10-7-8.0 × 10-6 mol/ L for ofloxacin and 1.0 × 10-7-3.0 × 10 -5 mol/L for ciprofloxacin, with detection limits of 3 × 10-8 mol/L, 5 × 10-8 mol/L and 3 × 10 -8 mol/L, respectively. The method was applied to the determination of fluoroquinolones in pharmaceutical preparations.",

keywords = "Chemiluminescence, Flow injection, Fluoroquinolones, Soluble manganese (IV)",

author = "Jianxiu Du and Yinhuan Li and Jiuru Lu",

year = "2005",

doi = "10.1002/bio.798",

language = "英语",

volume = "20",

pages = "30--35",

journal = "Luminescence",

issn = "1522-7235",

publisher = "John Wiley and Sons Ltd",

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TY - JOUR

T1 - Chemiluminescence determination of fluoroquinolone antibiotics using a soluble manganese (IV)-sulphite system

AU - Du, Jianxiu

AU - Li, Yinhuan

AU - Lu, Jiuru

PY - 2005

Y1 - 2005

N2 - The reaction of soluble manganese (IV) with sulphite in acidic condition was found to elicit weak chemiluminescence (CL). The CL signal was remarkably enhanced in the presence of three fluoroquinolones, viz. norfloxacin, ofloxacin and ciprofloxacin. Based on these observations, a new flow-injection CL method was developed for the determination of these fluoroquinolones. The method allows determination in the range 5.0 × 10-8-1.0 × 10 -6 mol/L for norfloxacin, 1.0 × 10-7-8.0 × 10-6 mol/ L for ofloxacin and 1.0 × 10-7-3.0 × 10 -5 mol/L for ciprofloxacin, with detection limits of 3 × 10-8 mol/L, 5 × 10-8 mol/L and 3 × 10 -8 mol/L, respectively. The method was applied to the determination of fluoroquinolones in pharmaceutical preparations.

AB - The reaction of soluble manganese (IV) with sulphite in acidic condition was found to elicit weak chemiluminescence (CL). The CL signal was remarkably enhanced in the presence of three fluoroquinolones, viz. norfloxacin, ofloxacin and ciprofloxacin. Based on these observations, a new flow-injection CL method was developed for the determination of these fluoroquinolones. The method allows determination in the range 5.0 × 10-8-1.0 × 10 -6 mol/L for norfloxacin, 1.0 × 10-7-8.0 × 10-6 mol/ L for ofloxacin and 1.0 × 10-7-3.0 × 10 -5 mol/L for ciprofloxacin, with detection limits of 3 × 10-8 mol/L, 5 × 10-8 mol/L and 3 × 10 -8 mol/L, respectively. The method was applied to the determination of fluoroquinolones in pharmaceutical preparations.

KW - Chemiluminescence

KW - Flow injection

KW - Fluoroquinolones

KW - Soluble manganese (IV)

UR - https://www.scopus.com/pages/publications/14744270702

U2 - 10.1002/bio.798

DO - 10.1002/bio.798

M3 - 文章

C2 - 15685664

AN - SCOPUS:14744270702

SN - 1522-7235

VL - 20

SP - 30

EP - 35

JO - Luminescence

JF - Luminescence

IS - 1

ER -

Chemiluminescence determination of fluoroquinolone antibiotics using a soluble manganese (IV)-sulphite system

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Keywords

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