TY - JOUR
T1 - Chemical Oxidative Potential and Cellular Oxidative Stress from Open Biomass Burning Aerosol
AU - Tuet, Wing Y.
AU - Liu, Fobang
AU - De Oliveira Alves, Nilmara
AU - Fok, Shierly
AU - Artaxo, Paulo
AU - Vasconcellos, Pérola
AU - Champion, Julie A.
AU - Ng, Nga L.
N1 - Publisher Copyright:
© 2019 American Chemical Society.
PY - 2019/3/12
Y1 - 2019/3/12
N2 - Particulate matter (PM) exposure is a leading global human health risk. In this study, water-soluble oxidative potential (OP) and intracellular reactive oxygen and nitrogen species (ROS/RNS) production were measured for open biomass burning aerosol collected from the Brazilian Amazon. Compared to ambient samples collected from Atlanta and laboratory-generated secondary organic aerosol (SOA), biomass burning aerosol had comparable OP and induced higher levels of ROS/RNS. Compared to regressed OP ranges for biomass burning factors resolved using source apportionment in prior studies, the samples investigated in this study spanned a wider OP range, suggesting that concentration addition may not be applicable for OP measurements. The discrepancy between ROS/RNS estimated using laboratory polycyclic aromatic hydrocarbons (PAHs) solution mixtures and ROS/RNS measured for the water-soluble hydrophobic fraction of Amazon filter samples further supports this conclusion. These results have important implications as many previous studies are based on linear regressions that assume concentration addition. Finally, a significant correlation was observed between ROS/RNS and levoglucosan concentrations although exposure to pure solutions of levoglucosan induced negligible ROS/RNS. These results demonstrate that levoglucosan may be considered as a predictor for ROS/RNS even though concentration addition may not be an applicable mixture effect model.
AB - Particulate matter (PM) exposure is a leading global human health risk. In this study, water-soluble oxidative potential (OP) and intracellular reactive oxygen and nitrogen species (ROS/RNS) production were measured for open biomass burning aerosol collected from the Brazilian Amazon. Compared to ambient samples collected from Atlanta and laboratory-generated secondary organic aerosol (SOA), biomass burning aerosol had comparable OP and induced higher levels of ROS/RNS. Compared to regressed OP ranges for biomass burning factors resolved using source apportionment in prior studies, the samples investigated in this study spanned a wider OP range, suggesting that concentration addition may not be applicable for OP measurements. The discrepancy between ROS/RNS estimated using laboratory polycyclic aromatic hydrocarbons (PAHs) solution mixtures and ROS/RNS measured for the water-soluble hydrophobic fraction of Amazon filter samples further supports this conclusion. These results have important implications as many previous studies are based on linear regressions that assume concentration addition. Finally, a significant correlation was observed between ROS/RNS and levoglucosan concentrations although exposure to pure solutions of levoglucosan induced negligible ROS/RNS. These results demonstrate that levoglucosan may be considered as a predictor for ROS/RNS even though concentration addition may not be an applicable mixture effect model.
UR - https://www.scopus.com/pages/publications/85062362491
U2 - 10.1021/acs.estlett.9b00060
DO - 10.1021/acs.estlett.9b00060
M3 - 文章
AN - SCOPUS:85062362491
SN - 2328-8930
VL - 6
SP - 126
EP - 132
JO - Environmental Science and Technology Letters
JF - Environmental Science and Technology Letters
IS - 3
ER -
