Cell membrane camouflaged magnetic nanoparticles as a biomimetic drug discovery platform

Yusi Bu; Qi Hu; Ruifang Ke; Yue Sui; Xiaoyu Xie; Sicen Wang

doi:10.1039/c8cc08530g

Cell membrane camouflaged magnetic nanoparticles as a biomimetic drug discovery platform

Yusi Bu
, Qi Hu
, Ruifang Ke
, Yue Sui
, Xiaoyu Xie
, Sicen Wang

Health Science Center

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

We report a novel biomimetic drug discovery platform using high expression epidermal growth factor receptor (EGFR) HEK 293 cell membrane camouflaged magnetic nanoparticles. The EGFR/magnetic cell membrane nanoparticles (MCMNs) integrated desirable magnetic features and special binding bioaffinity. Application of this drug-targeting concept is expected to pave ways to a new drug discovery strategy.

Original language	English
Pages (from-to)	13427-13430
Number of pages	4
Journal	Chemical Communications
Volume	54
Issue number	95
DOIs	https://doi.org/10.1039/c8cc08530g
State	Published - 2018

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title = "Cell membrane camouflaged magnetic nanoparticles as a biomimetic drug discovery platform",

abstract = "We report a novel biomimetic drug discovery platform using high expression epidermal growth factor receptor (EGFR) HEK 293 cell membrane camouflaged magnetic nanoparticles. The EGFR/magnetic cell membrane nanoparticles (MCMNs) integrated desirable magnetic features and special binding bioaffinity. Application of this drug-targeting concept is expected to pave ways to a new drug discovery strategy.",

author = "Yusi Bu and Qi Hu and Ruifang Ke and Yue Sui and Xiaoyu Xie and Sicen Wang",

note = "Publisher Copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/c8cc08530g",

language = "英语",

volume = "54",

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AU - Bu, Yusi

AU - Hu, Qi

AU - Ke, Ruifang

AU - Sui, Yue

AU - Xie, Xiaoyu

AU - Wang, Sicen

PY - 2018

Y1 - 2018

N2 - We report a novel biomimetic drug discovery platform using high expression epidermal growth factor receptor (EGFR) HEK 293 cell membrane camouflaged magnetic nanoparticles. The EGFR/magnetic cell membrane nanoparticles (MCMNs) integrated desirable magnetic features and special binding bioaffinity. Application of this drug-targeting concept is expected to pave ways to a new drug discovery strategy.

AB - We report a novel biomimetic drug discovery platform using high expression epidermal growth factor receptor (EGFR) HEK 293 cell membrane camouflaged magnetic nanoparticles. The EGFR/magnetic cell membrane nanoparticles (MCMNs) integrated desirable magnetic features and special binding bioaffinity. Application of this drug-targeting concept is expected to pave ways to a new drug discovery strategy.

UR - https://www.scopus.com/pages/publications/85057205260

U2 - 10.1039/c8cc08530g

DO - 10.1039/c8cc08530g

M3 - 文章

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AN - SCOPUS:85057205260

SN - 1359-7345

VL - 54

SP - 13427

EP - 13430

JO - Chemical Communications

JF - Chemical Communications

IS - 95

ER -

Cell membrane camouflaged magnetic nanoparticles as a biomimetic drug discovery platform

Abstract

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