Carrier-free, functionalized drug nanoparticles for targeted drug delivery

Wei Li; Yinlong Yang; Chao Wang; Zhuang Liu; Xiujuan Zhang; Feifei An; Xiaojun Diao; Xiaojun Hao; Xiaohong Zhang

doi:10.1039/c2cc33214k

Carrier-free, functionalized drug nanoparticles for targeted drug delivery

Wei Li
, Yinlong Yang
, Chao Wang
, Zhuang Liu
, Xiujuan Zhang
, Feifei An
, Xiaojun Diao
, Xiaojun Hao
, Xiaohong Zhang

Research output: Contribution to journal › Article › peer-review

75 Scopus citations

Abstract

We demonstrate a new concept of carrier-free functionalized drug nanoparticles for targeted drug delivery. It exhibits significantly enhanced drug efficacy to folate receptor-positive cells with high selectivity and a high drug loading content up to more than 78%.

Original language	English
Pages (from-to)	8120-8122
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	65
DOIs	https://doi.org/10.1039/c2cc33214k
State	Published - 18 Jul 2012
Externally published	Yes

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10.1039/c2cc33214k

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@article{b837dd8fff3d460dbfb3cd94909c629b,

title = "Carrier-free, functionalized drug nanoparticles for targeted drug delivery",

abstract = "We demonstrate a new concept of carrier-free functionalized drug nanoparticles for targeted drug delivery. It exhibits significantly enhanced drug efficacy to folate receptor-positive cells with high selectivity and a high drug loading content up to more than 78\%.",

author = "Wei Li and Yinlong Yang and Chao Wang and Zhuang Liu and Xiujuan Zhang and Feifei An and Xiaojun Diao and Xiaojun Hao and Xiaohong Zhang",

year = "2012",

month = jul,

day = "18",

doi = "10.1039/c2cc33214k",

language = "英语",

volume = "48",

pages = "8120--8122",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "65",

}

TY - JOUR

T1 - Carrier-free, functionalized drug nanoparticles for targeted drug delivery

AU - Li, Wei

AU - Yang, Yinlong

AU - Wang, Chao

AU - Liu, Zhuang

AU - Zhang, Xiujuan

AU - An, Feifei

AU - Diao, Xiaojun

AU - Hao, Xiaojun

AU - Zhang, Xiaohong

PY - 2012/7/18

Y1 - 2012/7/18

N2 - We demonstrate a new concept of carrier-free functionalized drug nanoparticles for targeted drug delivery. It exhibits significantly enhanced drug efficacy to folate receptor-positive cells with high selectivity and a high drug loading content up to more than 78%.

AB - We demonstrate a new concept of carrier-free functionalized drug nanoparticles for targeted drug delivery. It exhibits significantly enhanced drug efficacy to folate receptor-positive cells with high selectivity and a high drug loading content up to more than 78%.

UR - https://www.scopus.com/pages/publications/84864270312

U2 - 10.1039/c2cc33214k

DO - 10.1039/c2cc33214k

M3 - 文章

C2 - 22766919

AN - SCOPUS:84864270312

SN - 1359-7345

VL - 48

SP - 8120

EP - 8122

JO - Chemical Communications

JF - Chemical Communications

IS - 65

ER -

Carrier-free, functionalized drug nanoparticles for targeted drug delivery

Abstract

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