Abstract
Objective: To investigate the prevalence and clinical presentation, endoscopic aspect and gastric histology of cardia intestinal metaplasia (CIM). Methods: Biopsy specimens were taken from the 120 randomly selected patients undergoing routine diagnostic endoscopy. Eight biopsy specimens, taken from cardia, lower esophagus and gastric antrum, were stained with hematoxylin/eosin, alcian blue/periodic acid-Schiff, alcian blue/ high iron diamine and Gimenez, respectively. Results: CIM was found in 26 patients (21.67%), which was associated with increased age, atrophic gastritis and inflammation (P<0.05, P<0.01). Complete CIM was detected in 17 (14.2%) of the 120 subjects, and incomplete CIM subtype in 9 (7.5%). There was association of complete IM with carditis, H. pylori infection and antral intestinal metaplasia (P<0.05). Conclusion CIM is more common than Barrett's esophagus and increases in prevalence with age. Complete CIM is a manifestation of H. pylori infection associated with gastritis and multifocal atrophic gastritis.
| Original language | English |
|---|---|
| Pages (from-to) | 350-352 |
| Number of pages | 3 |
| Journal | Journal of Xi'an Jiaotong University (Medical Sciences) |
| Volume | 25 |
| Issue number | 4 |
| State | Published - Aug 2004 |
| Externally published | Yes |
Keywords
- Endoscopy
- Gastric cardia
- Intestinal metaplasia