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Bilateral purtscher-like retinopathy associated with DRESS syndrome: a case report

  • Langxuan Yuan
  • , Yuchen Li
  • , Hanze Zhang
  • , Yucen Hou
  • , Qianyan Kang
  • , Jianqin Lei
  • The First Affiliated Hospital of Xi’an Jiaotong University

Research output: Contribution to journalArticlepeer-review

Abstract

Background: To report a case of Bilateral Purtscher-like retinopathy associated with DRESS syndrome managed with ocular and systemic treatments. Case presentation: A 29-year-old healthy female developed multi-organ (cutaneous, hematologic, renal and hepatic) disfunction and profound vision loss 1 month after Human papillomavirus vaccine injection. At the first presentation, her visual acuity was counting fingers in both eyes. Fundus exam showed remarkable cotton-wool spots, retinal hemorrhages and macular edema. She was diagnosed DRESS syndrome and Purtscher-like retinopathy and treated with intravitreal injection of ranibizumab, systemic steroids anticoagulants, and plasma exchange. The patient finally recovered from this life-threatening condition but left with permanent visual damage. Conclusion: Purtscher-like retinopathy could be complicated by DRESS syndrome which is usually considered a type IV hypersensitivity reaction.

Original languageEnglish
Article number46
JournalJournal of Ophthalmic Inflammation and Infection
Volume14
Issue number1
DOIs
StatePublished - Dec 2024
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • DRESS syndrome
  • Delayed hypersensitivity reaction
  • Inflammatory storm
  • Purtscher-like retinopathy

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