B(C6F5)3-Catalyzed Decarboxylative Formation of Benzofurans via Intermolecular (3 + 2) Cyclization from Phenols

Xiao Shu; Yicheng He; Wusheng Guo

doi:10.1021/acs.orglett.5c02208

B(C₆F₅)₃-Catalyzed Decarboxylative Formation of Benzofurans via Intermolecular (3 + 2) Cyclization from Phenols

Xiao Shu
, Yicheng He
, Wusheng Guo

Frontier Institute of Science and Technology

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

Abstract

We herein report unprecedented B(C₆F₅)₃ catalyzed intermolecular (3 + 2) cyclizations enabling versatile construction of benzofurans from readily available methylene cyclic carbonates and phenols. Such an organocatalytic process tolerated well different functional groups and only generated water and CO₂ as byproducts. The reactions proved to be scalable, and the corresponding products could be transformed into value-added benzofuran derivatives via simple experimental operations.

Original language	English
Pages (from-to)	7242-7246
Number of pages	5
Journal	Organic Letters
Volume	27
Issue number	26
DOIs	https://doi.org/10.1021/acs.orglett.5c02208
State	Published - 4 Jul 2025

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abstract = "We herein report unprecedented B(C6F5)3 catalyzed intermolecular (3 + 2) cyclizations enabling versatile construction of benzofurans from readily available methylene cyclic carbonates and phenols. Such an organocatalytic process tolerated well different functional groups and only generated water and CO2 as byproducts. The reactions proved to be scalable, and the corresponding products could be transformed into value-added benzofuran derivatives via simple experimental operations.",

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AU - Shu, Xiao

AU - He, Yicheng

AU - Guo, Wusheng

PY - 2025/7/4

Y1 - 2025/7/4

N2 - We herein report unprecedented B(C6F5)3 catalyzed intermolecular (3 + 2) cyclizations enabling versatile construction of benzofurans from readily available methylene cyclic carbonates and phenols. Such an organocatalytic process tolerated well different functional groups and only generated water and CO2 as byproducts. The reactions proved to be scalable, and the corresponding products could be transformed into value-added benzofuran derivatives via simple experimental operations.

AB - We herein report unprecedented B(C6F5)3 catalyzed intermolecular (3 + 2) cyclizations enabling versatile construction of benzofurans from readily available methylene cyclic carbonates and phenols. Such an organocatalytic process tolerated well different functional groups and only generated water and CO2 as byproducts. The reactions proved to be scalable, and the corresponding products could be transformed into value-added benzofuran derivatives via simple experimental operations.

UR - https://www.scopus.com/pages/publications/105009269683

U2 - 10.1021/acs.orglett.5c02208

DO - 10.1021/acs.orglett.5c02208

M3 - 文章

C2 - 40569029

AN - SCOPUS:105009269683

SN - 1523-7060

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JO - Organic Letters

JF - Organic Letters

IS - 26

ER -

B(C₆F₅)₃-Catalyzed Decarboxylative Formation of Benzofurans via Intermolecular (3 + 2) Cyclization from Phenols

Abstract

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