Atypical presentation of tracheobronchopathia osteochondroplastica: Is chronic inflammation a perpetrator?

Asmitananda Thakur; Tian Yang; Tianjun Chen; Netra Rana; Bo Zhu; Xiaohong Wei; Lan Yang; Guanjun Zhang; Ming Zhang; Mingwei Chen

doi:10.1159/000346662

Atypical presentation of tracheobronchopathia osteochondroplastica: Is chronic inflammation a perpetrator?

Asmitananda Thakur
, Tian Yang
, Tianjun Chen
, Netra Rana
, Bo Zhu
, Xiaohong Wei
, Lan Yang
, Guanjun Zhang
, Ming Zhang
, Mingwei Chen

The First Affiliated Hospital of Xi’an Jiaotong University
Department of Pathology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Objective: To report an atypical presentation of tracheobronchopathia osteochondroplastica (TO). Clinical Presentation and Intervention: A 59-year-old man was investigated for productive cough of 1 month. An antimycobacterial combination regime was initiated with a misdiagnosis of endobronchial tuberculosis. At follow-up, the patient reported worsening of his symptoms. CT revealed an increased intensity of the cartilage ring surrounding the trachea, and bronchoscopy showed tracheal stenosis with white, hard nodules on the airway submucosa. Histopathology confirmed the diagnosis of TO. Conclusion: This case showed that TO should be considered in patients with cough not explained by noninvasive testing and not responsive to empiric medications.

Original language	English
Pages (from-to)	503-505
Number of pages	3
Journal	Medical Principles and Practice
Volume	22
Issue number	5
DOIs	https://doi.org/10.1159/000346662
State	Published - Sep 2013
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Airway inflammation
Bronchoscopy
Chronic cough
Nodule
Ossification
Tracheobronchopathia osteochondroplastica

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10.1159/000346662

Cite this

@article{ed397dc082cc4702a6d66b30ca9b9283,

title = "Atypical presentation of tracheobronchopathia osteochondroplastica: Is chronic inflammation a perpetrator?",

abstract = "Objective: To report an atypical presentation of tracheobronchopathia osteochondroplastica (TO). Clinical Presentation and Intervention: A 59-year-old man was investigated for productive cough of 1 month. An antimycobacterial combination regime was initiated with a misdiagnosis of endobronchial tuberculosis. At follow-up, the patient reported worsening of his symptoms. CT revealed an increased intensity of the cartilage ring surrounding the trachea, and bronchoscopy showed tracheal stenosis with white, hard nodules on the airway submucosa. Histopathology confirmed the diagnosis of TO. Conclusion: This case showed that TO should be considered in patients with cough not explained by noninvasive testing and not responsive to empiric medications.",

keywords = "Airway inflammation, Bronchoscopy, Chronic cough, Nodule, Ossification, Tracheobronchopathia osteochondroplastica",

author = "Asmitananda Thakur and Tian Yang and Tianjun Chen and Netra Rana and Bo Zhu and Xiaohong Wei and Lan Yang and Guanjun Zhang and Ming Zhang and Mingwei Chen",

year = "2013",

month = sep,

doi = "10.1159/000346662",

language = "英语",

volume = "22",

pages = "503--505",

journal = "Medical Principles and Practice",

issn = "1011-7571",

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}

TY - JOUR

T1 - Atypical presentation of tracheobronchopathia osteochondroplastica

T2 - Is chronic inflammation a perpetrator?

AU - Thakur, Asmitananda

AU - Yang, Tian

AU - Chen, Tianjun

AU - Rana, Netra

AU - Zhu, Bo

AU - Wei, Xiaohong

AU - Yang, Lan

AU - Zhang, Guanjun

AU - Zhang, Ming

AU - Chen, Mingwei

PY - 2013/9

Y1 - 2013/9

N2 - Objective: To report an atypical presentation of tracheobronchopathia osteochondroplastica (TO). Clinical Presentation and Intervention: A 59-year-old man was investigated for productive cough of 1 month. An antimycobacterial combination regime was initiated with a misdiagnosis of endobronchial tuberculosis. At follow-up, the patient reported worsening of his symptoms. CT revealed an increased intensity of the cartilage ring surrounding the trachea, and bronchoscopy showed tracheal stenosis with white, hard nodules on the airway submucosa. Histopathology confirmed the diagnosis of TO. Conclusion: This case showed that TO should be considered in patients with cough not explained by noninvasive testing and not responsive to empiric medications.

AB - Objective: To report an atypical presentation of tracheobronchopathia osteochondroplastica (TO). Clinical Presentation and Intervention: A 59-year-old man was investigated for productive cough of 1 month. An antimycobacterial combination regime was initiated with a misdiagnosis of endobronchial tuberculosis. At follow-up, the patient reported worsening of his symptoms. CT revealed an increased intensity of the cartilage ring surrounding the trachea, and bronchoscopy showed tracheal stenosis with white, hard nodules on the airway submucosa. Histopathology confirmed the diagnosis of TO. Conclusion: This case showed that TO should be considered in patients with cough not explained by noninvasive testing and not responsive to empiric medications.

KW - Airway inflammation

KW - Bronchoscopy

KW - Chronic cough

KW - Nodule

KW - Ossification

KW - Tracheobronchopathia osteochondroplastica

UR - https://www.scopus.com/pages/publications/84884286845

U2 - 10.1159/000346662

DO - 10.1159/000346662

M3 - 文章

C2 - 23428943

AN - SCOPUS:84884286845

SN - 1011-7571

VL - 22

SP - 503

EP - 505

JO - Medical Principles and Practice

JF - Medical Principles and Practice

IS - 5

ER -

Atypical presentation of tracheobronchopathia osteochondroplastica: Is chronic inflammation a perpetrator?

Abstract

UN SDGs

Keywords

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