Skip to main navigation Skip to search Skip to main content

Anatomy-guided brain pet imaging incorporating a joint prior model

  • Lijun Lu
  • , Jianhua Ma
  • , Jing Tang
  • , Qianjin Feng
  • , Arman Rahmim
  • , Wufan Chen
  • Southern Medical University
  • Oakland University
  • Johns Hopkins University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

We proposed a maximum a posterior (MAP) framework for incorporating information from co-registered anatomical images into PET image reconstruction through a novel anato-functional joint prior. The characteristic of the utilized hyperbolic potential function is determinate by the voxel intensity differences within the anatomical image, while the penalization is computed based on voxel intensity differences in reconstructed PET images. Using realistic simulated short time 18FDG PET scan data, we optimized the performance of the proposed MAP reconstruction with the joint prior (JP-MAP), and compared its performance with conventional 3D maximum likelihood expectation maximization (MLEM) and MAP reconstructions. The proposed JP-MAP reconstruction algorithm resulted in quantitatively enhanced reconstructed images, as demonstrated in extensive 18FDG PET simulation study.

Original languageEnglish
Title of host publication2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages959-962
Number of pages4
ISBN (Electronic)9781467319591
DOIs
StatePublished - 29 Jul 2014
Externally publishedYes
Event11th IEEE International Symposium on Biomedical Imaging, ISBI 2014 - Beijing, China
Duration: 29 Apr 20142 May 2014

Publication series

Name2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014

Conference

Conference11th IEEE International Symposium on Biomedical Imaging, ISBI 2014
Country/TerritoryChina
CityBeijing
Period29/04/142/05/14

Keywords

  • Anatomical priors
  • Joint prior
  • Maximum a posterior
  • Positron emission tomography

Fingerprint

Dive into the research topics of 'Anatomy-guided brain pet imaging incorporating a joint prior model'. Together they form a unique fingerprint.

Cite this