An integrated passive-flow microfluidic biosensor with organic photodiodes for ultra-sensitive pathogen detection in water

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

8 Scopus citations

Abstract

This work reports on integrated passive-flow optical microfluidic devices to detect waterborne pathogens in the field. Ring-shaped organic photodiodes were integrated to a capillary-induced flow microfluidic channel for monitoring chemiluminescent sandwich immunoassays enhanced by gold nanoparticles. The integrated device yielded a resolution of 4×104 cells/mL for the detection of Legionella pneumophila, which represented a 25-fold improvement over chemiluminescence detection devices employing no gold-nanoparticle enhancement. This work demonstrates the feasibility of a low-cost but highly sensitive lab-on-a-chip device amenable for point-of-use applications.

Original languageEnglish
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4411-4414
Number of pages4
ISBN (Electronic)9781424479290
DOIs
StatePublished - 2 Nov 2014
Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
Duration: 26 Aug 201430 Aug 2014

Publication series

Name2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014

Conference

Conference2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
Country/TerritoryUnited States
CityChicago
Period26/08/1430/08/14

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