An efficient procedure for the direct nucleophilic substitution of the abiko-masamune auxiliary

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Abstract

An efficient method for the nucleophilic displace-ment of the Abiko-Masamune auxiliary is reported, which involves i-PrMgCl for intermediate ester activation.

Original languageEnglish
Pages (from-to)2417-2420
Number of pages4
JournalSynlett
Issue number15
DOIs
StatePublished - 2009
Externally publishedYes

Keywords

  • Abiko-Masamune auxiliary
  • Aldol reaction
  • Ester cleavage
  • Lewis acid
  • Synthetic methodology

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