AgSCF3-Mediated Oxidative Trifluoromethythiolation of Alkynes with Dearomatization to Synthesize SCF3-Substituted Spiro[4,5]trienones

  • Dong Po Jin
  • , Pin Gao
  • , Dao Qian Chen
  • , Si Chen
  • , Jia Wang
  • , Xue Yuan Liu
  • , Yong Min Liang

Research output: Contribution to journalArticlepeer-review

127 Scopus citations

Abstract

A new method for the AgSCF3-mediated radical cascade difunctionalizing trifluoromethythiolation of alkynes with dearomatization is developed. This protocol provides a novel route to SCF3-substituted spirocyclic compounds via the formation of one C-SCF3 bond, one C-C bond, and one C-O double bond in a single step.

Original languageEnglish
Pages (from-to)3486-3489
Number of pages4
JournalOrganic Letters
Volume18
Issue number14
DOIs
StatePublished - 15 Jul 2016

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