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[Advances in the studies of androgen metabolism and de novo androgen synthesis in castration resistant prostate cancer].

  • Xi'an Jiaotong University

Research output: Contribution to journalReview articlepeer-review

Abstract

Prostate cancer generally relapses into castration resistant prostate cancer (CRPC) after androgen deprivation therapy, which may be associated with androgen metabolism, particularly de novo androgen synthesis apart from the amplification and mutation of androgen receptor and the activation of its signaling pathways. This article focuses on the advances in the studies of the changes in androgen metabolism and de novo androgen synthesis in CRPC as well as their possible mechanisms and clinical significance.

Original languageEnglish
Pages (from-to)736-741
Number of pages6
JournalZhonghua nan ke xue = National journal of andrology
Volume19
Issue number8
StatePublished - Aug 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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