Advances in the assembly model of bacterial type IVB secretion systems

Shan Wang; Dan Wang; Dan Du; Shanshan Li; Wei Yan

doi:10.3390/app8122369

Advances in the assembly model of bacterial type IVB secretion systems

Shan Wang
, Dan Wang
, Dan Du
, Shanshan Li
, Wei Yan

School of Energy and Power Engineering

Xi'an Jiaotong University

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Bacterial type IV secretion systems (T4SSs) are related to not only secretion of effector proteins and virulence factors, but also to bacterial conjugation systems that promote bacterial horizontal gene transfer. The subgroup T4BSS, with a unique mosaic architecture system, consists of nearly 30 proteins that are similar to those from other secretory systems. Despite being intensively studied, the secretion mechanism of T4BSS remains unclear. This review systematically summarizes the protein composition, coding gene set, core complex, and protein interactions of T4BSS. The interactions of proteins in the core complex of the system and the operation mechanism between each element needs to be further studied.

Original language	English
Article number	2368
Journal	Applied Sciences (Switzerland)
Volume	8
Issue number	12
DOIs	https://doi.org/10.3390/app8122369
State	Published - 23 Nov 2018

Keywords

Core complex
Mosaic architecture
T4BSS

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10.3390/app8122369

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title = "Advances in the assembly model of bacterial type IVB secretion systems",

abstract = "Bacterial type IV secretion systems (T4SSs) are related to not only secretion of effector proteins and virulence factors, but also to bacterial conjugation systems that promote bacterial horizontal gene transfer. The subgroup T4BSS, with a unique mosaic architecture system, consists of nearly 30 proteins that are similar to those from other secretory systems. Despite being intensively studied, the secretion mechanism of T4BSS remains unclear. This review systematically summarizes the protein composition, coding gene set, core complex, and protein interactions of T4BSS. The interactions of proteins in the core complex of the system and the operation mechanism between each element needs to be further studied.",

keywords = "Core complex, Mosaic architecture, T4BSS",

author = "Shan Wang and Dan Wang and Dan Du and Shanshan Li and Wei Yan",

note = "Publisher Copyright: {\textcopyright} 2018 by the authors.",

year = "2018",

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doi = "10.3390/app8122369",

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journal = "Applied Sciences (Switzerland)",

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TY - JOUR

T1 - Advances in the assembly model of bacterial type IVB secretion systems

AU - Wang, Shan

AU - Wang, Dan

AU - Du, Dan

AU - Li, Shanshan

AU - Yan, Wei

PY - 2018/11/23

Y1 - 2018/11/23

N2 - Bacterial type IV secretion systems (T4SSs) are related to not only secretion of effector proteins and virulence factors, but also to bacterial conjugation systems that promote bacterial horizontal gene transfer. The subgroup T4BSS, with a unique mosaic architecture system, consists of nearly 30 proteins that are similar to those from other secretory systems. Despite being intensively studied, the secretion mechanism of T4BSS remains unclear. This review systematically summarizes the protein composition, coding gene set, core complex, and protein interactions of T4BSS. The interactions of proteins in the core complex of the system and the operation mechanism between each element needs to be further studied.

AB - Bacterial type IV secretion systems (T4SSs) are related to not only secretion of effector proteins and virulence factors, but also to bacterial conjugation systems that promote bacterial horizontal gene transfer. The subgroup T4BSS, with a unique mosaic architecture system, consists of nearly 30 proteins that are similar to those from other secretory systems. Despite being intensively studied, the secretion mechanism of T4BSS remains unclear. This review systematically summarizes the protein composition, coding gene set, core complex, and protein interactions of T4BSS. The interactions of proteins in the core complex of the system and the operation mechanism between each element needs to be further studied.

KW - Core complex

KW - Mosaic architecture

KW - T4BSS

UR - https://www.scopus.com/pages/publications/85057277328

U2 - 10.3390/app8122369

DO - 10.3390/app8122369

M3 - 文献综述

AN - SCOPUS:85057277328

SN - 2076-3417

VL - 8

JO - Applied Sciences (Switzerland)

JF - Applied Sciences (Switzerland)

IS - 12

M1 - 2368

ER -

Advances in the assembly model of bacterial type IVB secretion systems

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Keywords

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