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Adaptive L1/2 shooting regularization method for survival analysis using gene expression data

  • Xiao Ying Liu
  • , Yong Liang
  • , Zong Ben Xu
  • , Hai Zhang
  • , Kwong Sak Leung
  • Macau University of Science and Technology
  • Xi'an Jiaotong University
  • Chinese University of Hong Kong

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

A new adaptive L1/2 shooting regularization method for variable selection based on the Cox's proportional hazards mode being proposed. This adaptive L1/2 shooting algorithm can be easily obtained by the optimization of a reweighed iterative series of L1 penalties and a shooting strategy of L1/2 penalty. Simulation results based on high dimensional artificial data show that the adaptive L1/2 shooting regularization method can be more accurate for variable selection than Lasso and adaptive Lasso methods. The results from real gene expression dataset (DLBCL) also indicate that the L1/2 regularization method performs competitively.

Original languageEnglish
Article number475702
JournalScientific World Journal
Volume2013
DOIs
StatePublished - 2013

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