Activated ERK: An Emerging Player in miRNA Downregulation

Yiping Qu; Bingyin Shi; Peng Hou

doi:10.1016/j.trecan.2017.01.002

Activated ERK: An Emerging Player in miRNA Downregulation

Yiping Qu
, Bingyin Shi
, Peng Hou

The First Affiliated Hospital of Xi’an Jiaotong University

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

To date, the mechanisms underlying global downregulation of miRNAs in cancer remain largely unclear. Recent findings indicate that activated ERK can cause widespread miRNA repression through suppressing the major steps of miRNA biogenesis. Here we discuss how ERK signaling globally downregulates miRNAs and how this contributes to tumorigenesis.

Original language	English
Pages (from-to)	163-165
Number of pages	3
Journal	Trends in Cancer
Volume	3
Issue number	3
DOIs	https://doi.org/10.1016/j.trecan.2017.01.002
State	Published - 1 Mar 2017
Externally published	Yes

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10.1016/j.trecan.2017.01.002

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@article{53cb1b610ba54990817af3b62b025a3d,

title = "Activated ERK: An Emerging Player in miRNA Downregulation",

abstract = "To date, the mechanisms underlying global downregulation of miRNAs in cancer remain largely unclear. Recent findings indicate that activated ERK can cause widespread miRNA repression through suppressing the major steps of miRNA biogenesis. Here we discuss how ERK signaling globally downregulates miRNAs and how this contributes to tumorigenesis.",

author = "Yiping Qu and Bingyin Shi and Peng Hou",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

year = "2017",

month = mar,

day = "1",

doi = "10.1016/j.trecan.2017.01.002",

language = "英语",

volume = "3",

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journal = "Trends in Cancer",

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TY - JOUR

T1 - Activated ERK

T2 - An Emerging Player in miRNA Downregulation

AU - Qu, Yiping

AU - Shi, Bingyin

AU - Hou, Peng

PY - 2017/3/1

Y1 - 2017/3/1

N2 - To date, the mechanisms underlying global downregulation of miRNAs in cancer remain largely unclear. Recent findings indicate that activated ERK can cause widespread miRNA repression through suppressing the major steps of miRNA biogenesis. Here we discuss how ERK signaling globally downregulates miRNAs and how this contributes to tumorigenesis.

AB - To date, the mechanisms underlying global downregulation of miRNAs in cancer remain largely unclear. Recent findings indicate that activated ERK can cause widespread miRNA repression through suppressing the major steps of miRNA biogenesis. Here we discuss how ERK signaling globally downregulates miRNAs and how this contributes to tumorigenesis.

UR - https://www.scopus.com/pages/publications/85009473639

U2 - 10.1016/j.trecan.2017.01.002

DO - 10.1016/j.trecan.2017.01.002

M3 - 短篇评述

C2 - 28718429

AN - SCOPUS:85009473639

SN - 2405-8033

VL - 3

SP - 163

EP - 165

JO - Trends in Cancer

JF - Trends in Cancer

IS - 3

ER -

Activated ERK: An Emerging Player in miRNA Downregulation

Abstract

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