Access to azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition with exclusive regioselectivity

Yin Liu; Yicheng He; Yang Liu; Kun Wei; Wusheng Guo

doi:10.1039/d1qo01405f

Access to azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition with exclusive regioselectivity

Yin Liu
, Yicheng He
, Yang Liu
, Kun Wei
, Wusheng Guo

Frontier Institute of Science and Technology

South China University of Technology
Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

A highly efficient approach for the synthesis of azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition has been developed. This procedure utilizes methylene cyclic carbonates as a C5-dipole and 1-azadiene as a C4-synthon. The reactions could be performed at room temperature. The protocol features wide functional group tolerance with exclusive regioselectivity and generates CO2 as the only byproduct.

Original language	English
Pages (from-to)	7004-7008
Number of pages	5
Journal	Organic Chemistry Frontiers
Volume	8
Issue number	24
DOIs	https://doi.org/10.1039/d1qo01405f
State	Published - 21 Dec 2021

Access to Document

10.1039/d1qo01405f

Cite this

@article{765e745e29fc43529ff01dcfe298c1b1,

title = "Access to azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition with exclusive regioselectivity",

abstract = "A highly efficient approach for the synthesis of azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition has been developed. This procedure utilizes methylene cyclic carbonates as a C5-dipole and 1-azadiene as a C4-synthon. The reactions could be performed at room temperature. The protocol features wide functional group tolerance with exclusive regioselectivity and generates CO2 as the only byproduct.",

author = "Yin Liu and Yicheng He and Yang Liu and Kun Wei and Wusheng Guo",

note = "Publisher Copyright: {\textcopyright} the Partner Organisations.",

year = "2021",

month = dec,

day = "21",

doi = "10.1039/d1qo01405f",

language = "英语",

volume = "8",

pages = "7004--7008",

journal = "Organic Chemistry Frontiers",

issn = "2052-4110",

publisher = "Royal Society of Chemistry",

number = "24",

}

TY - JOUR

T1 - Access to azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition with exclusive regioselectivity

AU - Liu, Yin

AU - He, Yicheng

AU - Liu, Yang

AU - Wei, Kun

AU - Guo, Wusheng

PY - 2021/12/21

Y1 - 2021/12/21

N2 - A highly efficient approach for the synthesis of azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition has been developed. This procedure utilizes methylene cyclic carbonates as a C5-dipole and 1-azadiene as a C4-synthon. The reactions could be performed at room temperature. The protocol features wide functional group tolerance with exclusive regioselectivity and generates CO2 as the only byproduct.

AB - A highly efficient approach for the synthesis of azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition has been developed. This procedure utilizes methylene cyclic carbonates as a C5-dipole and 1-azadiene as a C4-synthon. The reactions could be performed at room temperature. The protocol features wide functional group tolerance with exclusive regioselectivity and generates CO2 as the only byproduct.

UR - https://www.scopus.com/pages/publications/85121033738

U2 - 10.1039/d1qo01405f

DO - 10.1039/d1qo01405f

M3 - 文章

AN - SCOPUS:85121033738

SN - 2052-4110

VL - 8

SP - 7004

EP - 7008

JO - Organic Chemistry Frontiers

JF - Organic Chemistry Frontiers

IS - 24

ER -

Access to azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition with exclusive regioselectivity

Abstract

Access to Document

Other files and links

Fingerprint

Cite this