Acceptorless Dehydrogenation of N-Heterocycles by Merging Visible-Light Photoredox Catalysis and Cobalt Catalysis

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Abstract

Herein, the first acceptorless dehydrogenation of tetrahydroquinolines (THQs), indolines, and other related N-heterocycles, by merging visible-light photoredox catalysis and cobalt catalysis at ambient temperature, is described. The potential applications to organic transformations and hydrogen-storage materials are demonstrated. Primary mechanistic investigations indicate that the catalytic cycle occurs predominantly by an oxidative quenching pathway.

Original languageEnglish
Pages (from-to)3080-3084
Number of pages5
JournalAngewandte Chemie - International Edition
Volume56
Issue number11
DOIs
StatePublished - 6 Mar 2017

Keywords

  • cobalt
  • dehydrogenation
  • heterocycles
  • photochemistry
  • reaction mechanisms

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