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A portable triboelectric spirometer for wireless pulmonary function monitoring

  • Qinghao Xu
  • , Yunsheng Fang
  • , Qingshen Jing
  • , Ning Hu
  • , Ke Lin
  • , Yifan Pan
  • , Lin Xu
  • , Haiqi Gao
  • , Ming Yuan
  • , Liang Chu
  • , Yanwen Ma
  • , Yannan Xie
  • , Jun Chen
  • , Lianhui Wang
  • Nanjing University of Posts and Telecommunications
  • University of California at Los Angeles
  • University of Cambridge
  • University of Southern California
  • Nanjing Normal University

Research output: Contribution to journalArticlepeer-review

132 Scopus citations

Abstract

Coronavirus disease 2019 (COVID-19) as a severe acute respiratory syndrome infection has spread rapidly across the world since its emergence in 2019 and drastically altered our way of life. Patients who have recovered from COVID-19 may still face persisting respiratory damage from the virus, necessitating long-term supervision after discharge to closely assess pulmonary function during rehabilitation. Therefore, developing portable spirometers for pulmonary function tests is of great significance for convenient home-based monitoring during recovery. Here, we propose a wireless, portable pulmonary function monitor for rehabilitation care after COVID-19. It is composed of a breath-to-electrical (BTE) sensor, a signal processing circuit, and a Bluetooth communication unit. The BTE sensor, with a compact size and light weight of 2.5 cm3 and 1.8 g respectively, is capable of converting respiratory biomechanical motions into considerable electrical signals. The output signal stability is greater than 93% under 35%–81% humidity, which allows for ideal expiration airflow sensing. Through a wireless communication circuit system, the signals can be received by a mobile terminal and processed into important physiological parameters, such as forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). The FEV1/FVC ratio is then calculated to further evaluate pulmonary function of testers. Through these measurement methods, the acquired pulmonary function parameters are shown to exhibit high accuracy (>97%) in comparison to a commercial spirometer. The practical design of the self-powered flow spirometer presents a low-cost and convenient method for pulmonary function monitoring during rehabilitation from COVID-19.

Original languageEnglish
Article number113329
JournalBiosensors and Bioelectronics
Volume187
DOIs
StatePublished - 1 Sep 2021
Externally publishedYes

Keywords

  • COVID-19
  • Pulmonary function tests
  • Self-powered sensors
  • Spirometers
  • Triboelectric nanogenerators

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