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A novel L1/2 regularization shooting method for Cox's proportional hazards model

  • Xin Ze Luan
  • , Yong Liang
  • , Cheng Liu
  • , Kwong Sak Leung
  • , Tak Ming Chan
  • , Zong Ben Xu
  • , Hai Zhang
  • Macau University of Science and Technology
  • Chinese University of Hong Kong
  • Xi'an Jiaotong University

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Nowadays, a series of methods are based on a L 1 penalty to solve the variable selection problem for a Cox's proportional hazards model. In 2010, Xu et al. have proposed a L 1/2 regularization and proved that the L 1/2 penalty is sparser than the L 1 penalty in linear regression models. In this paper, we propose a novel shooting method for the L 1/2 regularization and apply it on the Cox model for variable selection. The experimental results based on comprehensive simulation studies, real Primary Biliary Cirrhosis and diffuse large B cell lymphoma datasets show that the L 1/2 regularization shooting method performs competitively.

Original languageEnglish
Pages (from-to)143-152
Number of pages10
JournalSoft Computing
Volume18
Issue number1
DOIs
StatePublished - Jan 2014

Keywords

  • Cox model
  • Lasso
  • Variable selection

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