A hypergraph transformer method for brain disease diagnosis

  • Xiangmin Han
  • , Jingxi Feng
  • , Heming Xu
  • , Shaoyi Du
  • , Junchang Li

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Objective: To address the high-order correlation modeling and fusion challenges between functional and structural brain networks. Method: This paper proposes a hypergraph transformer method for modeling high-order correlations between functional and structural brain networks. By utilizing hypergraphs, we can effectively capture the high-order correlations within brain networks. The Transformer model provides robust feature extraction and integration capabilities that are capable of handling complex multimodal brain imaging. Results: The proposed method is evaluated on the ABIDE and ADNI datasets. It outperforms all the comparison methods, including traditional and graph-based methods, in diagnosing different types of brain diseases. The experimental results demonstrate its potential and application prospects in clinical practice. Conclusion: The proposed method provides new tools and insights for brain disease diagnosis, improving accuracy and aiding in understanding complex brain network relationships, thus laying a foundation for future brain science research.

Original languageEnglish
Article number1496573
JournalFrontiers in Medicine
Volume11
DOIs
StatePublished - 2024

Keywords

  • brain disease diagnosis
  • brain network
  • high-order correlation
  • hypergraph computation
  • transformer

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