A GSH-activatable ruthenium(ii)-azo photosensitizer for two-photon photodynamic therapy

Leli Zeng; Shi Kuang; Guanying Li; Chengzhi Jin; Liangnian Ji; Hui Chao

doi:10.1039/c6cc10330h

A GSH-activatable ruthenium(ii)-azo photosensitizer for two-photon photodynamic therapy

Leli Zeng
, Shi Kuang
, Guanying Li
, Chengzhi Jin
, Liangnian Ji
, Hui Chao

Sun Yat-Sen University

Research output: Contribution to journal › Article › peer-review

107 Scopus citations

Abstract

A glutathione (GSH)-activatable ruthenium(ii)-azo photosensitizer was prepared. The complex had low toxicity towards cells under dark conditions. It exhibited excellent phototoxicity under two-photon excitation (810 nm) and thus was developed as a two-photon photodynamic anticancer agent for cancer therapy.

Original language	English
Pages (from-to)	1977-1980
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	12
DOIs	https://doi.org/10.1039/c6cc10330h
State	Published - 2017
Externally published	Yes

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10.1039/c6cc10330h

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@article{b238433d54b740ceb716e6456295fd25,

title = "A GSH-activatable ruthenium(ii)-azo photosensitizer for two-photon photodynamic therapy",

abstract = "A glutathione (GSH)-activatable ruthenium(ii)-azo photosensitizer was prepared. The complex had low toxicity towards cells under dark conditions. It exhibited excellent phototoxicity under two-photon excitation (810 nm) and thus was developed as a two-photon photodynamic anticancer agent for cancer therapy.",

author = "Leli Zeng and Shi Kuang and Guanying Li and Chengzhi Jin and Liangnian Ji and Hui Chao",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2017",

doi = "10.1039/c6cc10330h",

language = "英语",

volume = "53",

pages = "1977--1980",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - A GSH-activatable ruthenium(ii)-azo photosensitizer for two-photon photodynamic therapy

AU - Zeng, Leli

AU - Kuang, Shi

AU - Li, Guanying

AU - Jin, Chengzhi

AU - Ji, Liangnian

AU - Chao, Hui

N1 - Publisher Copyright: © The Royal Society of Chemistry.

PY - 2017

Y1 - 2017

N2 - A glutathione (GSH)-activatable ruthenium(ii)-azo photosensitizer was prepared. The complex had low toxicity towards cells under dark conditions. It exhibited excellent phototoxicity under two-photon excitation (810 nm) and thus was developed as a two-photon photodynamic anticancer agent for cancer therapy.

AB - A glutathione (GSH)-activatable ruthenium(ii)-azo photosensitizer was prepared. The complex had low toxicity towards cells under dark conditions. It exhibited excellent phototoxicity under two-photon excitation (810 nm) and thus was developed as a two-photon photodynamic anticancer agent for cancer therapy.

UR - https://www.scopus.com/pages/publications/85011933973

U2 - 10.1039/c6cc10330h

DO - 10.1039/c6cc10330h

M3 - 文章

C2 - 28119967

AN - SCOPUS:85011933973

SN - 1359-7345

VL - 53

SP - 1977

EP - 1980

JO - Chemical Communications

JF - Chemical Communications

IS - 12

ER -

A GSH-activatable ruthenium(ii)-azo photosensitizer for two-photon photodynamic therapy

Abstract

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