A facile one-pot synthesis of acrylated hyaluronic acid

A. Sigen; Qian Xu; Peter McMichael; Yongsheng Gao; Xiaolin Li; Xi Wang; Udo Greiser; Dezhong Zhou; Wenxin Wang

doi:10.1039/c7cc08648b

A facile one-pot synthesis of acrylated hyaluronic acid

A. Sigen
, Qian Xu
, Peter McMichael
, Yongsheng Gao
, Xiaolin Li
, Xi Wang
, Udo Greiser
, Dezhong Zhou
, Wenxin Wang

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

The synthesis of acrylated hyaluronic acid (HA-A) normally requires 2 to 3 steps of modification, needs laborious purification and also increases the risks of HA degradation. Here, we report that the conjugation of acrylate groups to hyaluronic acid can be successfully achieved via a new facile one-pot approach. Two types of new HA-A hydrogels (via chemical or UV crosslinking) were developed and applied for 3D cell encapsulation.

Original language	English
Pages (from-to)	1081-1084
Number of pages	4
Journal	Chemical Communications
Volume	54
Issue number	9
DOIs	https://doi.org/10.1039/c7cc08648b
State	Published - 2018
Externally published	Yes

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title = "A facile one-pot synthesis of acrylated hyaluronic acid",

abstract = "The synthesis of acrylated hyaluronic acid (HA-A) normally requires 2 to 3 steps of modification, needs laborious purification and also increases the risks of HA degradation. Here, we report that the conjugation of acrylate groups to hyaluronic acid can be successfully achieved via a new facile one-pot approach. Two types of new HA-A hydrogels (via chemical or UV crosslinking) were developed and applied for 3D cell encapsulation.",

author = "A. Sigen and Qian Xu and Peter McMichael and Yongsheng Gao and Xiaolin Li and Xi Wang and Udo Greiser and Dezhong Zhou and Wenxin Wang",

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T1 - A facile one-pot synthesis of acrylated hyaluronic acid

AU - Sigen, A.

AU - Xu, Qian

AU - McMichael, Peter

AU - Gao, Yongsheng

AU - Li, Xiaolin

AU - Wang, Xi

AU - Greiser, Udo

AU - Zhou, Dezhong

AU - Wang, Wenxin

PY - 2018

Y1 - 2018

N2 - The synthesis of acrylated hyaluronic acid (HA-A) normally requires 2 to 3 steps of modification, needs laborious purification and also increases the risks of HA degradation. Here, we report that the conjugation of acrylate groups to hyaluronic acid can be successfully achieved via a new facile one-pot approach. Two types of new HA-A hydrogels (via chemical or UV crosslinking) were developed and applied for 3D cell encapsulation.

AB - The synthesis of acrylated hyaluronic acid (HA-A) normally requires 2 to 3 steps of modification, needs laborious purification and also increases the risks of HA degradation. Here, we report that the conjugation of acrylate groups to hyaluronic acid can be successfully achieved via a new facile one-pot approach. Two types of new HA-A hydrogels (via chemical or UV crosslinking) were developed and applied for 3D cell encapsulation.

UR - https://www.scopus.com/pages/publications/85041217562

U2 - 10.1039/c7cc08648b

DO - 10.1039/c7cc08648b

M3 - 文章

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AN - SCOPUS:85041217562

SN - 1359-7345

VL - 54

SP - 1081

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JO - Chemical Communications

JF - Chemical Communications

IS - 9

ER -

A facile one-pot synthesis of acrylated hyaluronic acid

Abstract

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