A facile method for the synthesis of partially O-methylated alditol acetate standards for GC-MS analysis of galactofuranose-containing structures

Jian Yu He; Yu Na Guo; Ling Ling Zhang; Lin Hong Huang

doi:10.1016/j.carres.2013.06.005

A facile method for the synthesis of partially O-methylated alditol acetate standards for GC-MS analysis of galactofuranose-containing structures

Jian Yu He
, Yu Na Guo
, Ling Ling Zhang
, Lin Hong Huang

Faculty of Electronic and Information Engineering

Xi'an Jiaotong University
Northwest University China

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Mixtures of partially O-methylated alditol acetate standards of galactofuranose were synthesized rapidly. Methyl galactofuranosides were obtained with a yield of 79.9% within 4 h under optimized reaction conditions. Methylation of methyl glycosides was carried out in the presence of BaO/Ba(OH)₂·8H₂O, giving rise to mixtures of partially methylated glycosides. The batch containing the most diverse structures of methyl ethers was converted into partially O-methylated alditol acetates (PMAAs) and then subjected to GC-MS. These PMAAs could be used as GC-MS standards for simultaneous identification of galactofuranose units with diverse linkages in complex carbohydrates.

Original language	English
Pages (from-to)	18-20
Number of pages	3
Journal	Carbohydrate Research
Volume	379
DOIs	https://doi.org/10.1016/j.carres.2013.06.005
State	Published - 2013

Keywords

GC-MS standards
Galactofuranose-containing structures
Methylation analysis
Partially O-methylated alditol acetates

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10.1016/j.carres.2013.06.005

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title = "A facile method for the synthesis of partially O-methylated alditol acetate standards for GC-MS analysis of galactofuranose-containing structures",

abstract = "Mixtures of partially O-methylated alditol acetate standards of galactofuranose were synthesized rapidly. Methyl galactofuranosides were obtained with a yield of 79.9\% within 4 h under optimized reaction conditions. Methylation of methyl glycosides was carried out in the presence of BaO/Ba(OH)2·8H2O, giving rise to mixtures of partially methylated glycosides. The batch containing the most diverse structures of methyl ethers was converted into partially O-methylated alditol acetates (PMAAs) and then subjected to GC-MS. These PMAAs could be used as GC-MS standards for simultaneous identification of galactofuranose units with diverse linkages in complex carbohydrates.",

keywords = "GC-MS standards, Galactofuranose-containing structures, Methylation analysis, Partially O-methylated alditol acetates",

author = "He, \{Jian Yu\} and Guo, \{Yu Na\} and Zhang, \{Ling Ling\} and Huang, \{Lin Hong\}",

year = "2013",

doi = "10.1016/j.carres.2013.06.005",

language = "英语",

volume = "379",

pages = "18--20",

journal = "Carbohydrate Research",

issn = "0008-6215",

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T1 - A facile method for the synthesis of partially O-methylated alditol acetate standards for GC-MS analysis of galactofuranose-containing structures

AU - He, Jian Yu

AU - Guo, Yu Na

AU - Zhang, Ling Ling

AU - Huang, Lin Hong

PY - 2013

Y1 - 2013

N2 - Mixtures of partially O-methylated alditol acetate standards of galactofuranose were synthesized rapidly. Methyl galactofuranosides were obtained with a yield of 79.9% within 4 h under optimized reaction conditions. Methylation of methyl glycosides was carried out in the presence of BaO/Ba(OH)2·8H2O, giving rise to mixtures of partially methylated glycosides. The batch containing the most diverse structures of methyl ethers was converted into partially O-methylated alditol acetates (PMAAs) and then subjected to GC-MS. These PMAAs could be used as GC-MS standards for simultaneous identification of galactofuranose units with diverse linkages in complex carbohydrates.

AB - Mixtures of partially O-methylated alditol acetate standards of galactofuranose were synthesized rapidly. Methyl galactofuranosides were obtained with a yield of 79.9% within 4 h under optimized reaction conditions. Methylation of methyl glycosides was carried out in the presence of BaO/Ba(OH)2·8H2O, giving rise to mixtures of partially methylated glycosides. The batch containing the most diverse structures of methyl ethers was converted into partially O-methylated alditol acetates (PMAAs) and then subjected to GC-MS. These PMAAs could be used as GC-MS standards for simultaneous identification of galactofuranose units with diverse linkages in complex carbohydrates.

KW - GC-MS standards

KW - Galactofuranose-containing structures

KW - Methylation analysis

KW - Partially O-methylated alditol acetates

UR - https://www.scopus.com/pages/publications/84880183973

U2 - 10.1016/j.carres.2013.06.005

DO - 10.1016/j.carres.2013.06.005

M3 - 文章

C2 - 23835470

AN - SCOPUS:84880183973

SN - 0008-6215

VL - 379

SP - 18

EP - 20

JO - Carbohydrate Research

JF - Carbohydrate Research

ER -

A facile method for the synthesis of partially O-methylated alditol acetate standards for GC-MS analysis of galactofuranose-containing structures

Abstract

Keywords

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