A facile method for purifying DNA-modified small particles and soft materials using aqueous two-phase systems

Xiaoman Duan; Biwu Liu

doi:10.1039/d3cc02350h

A facile method for purifying DNA-modified small particles and soft materials using aqueous two-phase systems

Xiaoman Duan
, Biwu Liu

School of Life Science and Technology (SLST)

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We herein report a convenient and effective method for the purification of DNA-conjugated materials with a benchtop minicentrifuge. We demonstrate the fast isolation of DNA-modified small gold nanoparticles (5 nm), liposomes, and DNA nanostructures using fluorescent methods and gel electrophoresis. Our method is cost-effective and efficient and would accelerate the development of DNA nanotechnology.

Original language	English
Pages (from-to)	9130-9133
Number of pages	4
Journal	Chemical Communications
Volume	59
Issue number	59
DOIs	https://doi.org/10.1039/d3cc02350h
State	Published - 27 Jun 2023

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title = "A facile method for purifying DNA-modified small particles and soft materials using aqueous two-phase systems",

abstract = "We herein report a convenient and effective method for the purification of DNA-conjugated materials with a benchtop minicentrifuge. We demonstrate the fast isolation of DNA-modified small gold nanoparticles (5 nm), liposomes, and DNA nanostructures using fluorescent methods and gel electrophoresis. Our method is cost-effective and efficient and would accelerate the development of DNA nanotechnology.",

author = "Xiaoman Duan and Biwu Liu",

note = "Publisher Copyright: {\textcopyright} 2023 The Royal Society of Chemistry.",

year = "2023",

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doi = "10.1039/d3cc02350h",

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T1 - A facile method for purifying DNA-modified small particles and soft materials using aqueous two-phase systems

AU - Duan, Xiaoman

AU - Liu, Biwu

PY - 2023/6/27

Y1 - 2023/6/27

N2 - We herein report a convenient and effective method for the purification of DNA-conjugated materials with a benchtop minicentrifuge. We demonstrate the fast isolation of DNA-modified small gold nanoparticles (5 nm), liposomes, and DNA nanostructures using fluorescent methods and gel electrophoresis. Our method is cost-effective and efficient and would accelerate the development of DNA nanotechnology.

AB - We herein report a convenient and effective method for the purification of DNA-conjugated materials with a benchtop minicentrifuge. We demonstrate the fast isolation of DNA-modified small gold nanoparticles (5 nm), liposomes, and DNA nanostructures using fluorescent methods and gel electrophoresis. Our method is cost-effective and efficient and would accelerate the development of DNA nanotechnology.

UR - https://www.scopus.com/pages/publications/85165306917

U2 - 10.1039/d3cc02350h

DO - 10.1039/d3cc02350h

M3 - 文章

C2 - 37409364

AN - SCOPUS:85165306917

SN - 1359-7345

VL - 59

SP - 9130

EP - 9133

JO - Chemical Communications

JF - Chemical Communications

IS - 59

ER -

A facile method for purifying DNA-modified small particles and soft materials using aqueous two-phase systems

Abstract

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