@inproceedings{b772bb24cf98483b9987440d9d704218,
title = "A classification of alternatively spliced cassette exons using AdaBoost-based algorithm",
abstract = "Alternative splicing (AS) is a mechanism for generating different gene transcripts (called isoforms) from the same genomic sequence. Accurate classification of alternative splicing is important for understanding the mechanism of gene regulation. Although the different algorithms are applied to classify AS, the accuracy of these algorithms are still unsatisfactory. In this paper, we propose a new classification algorithm to classify the cassette exons and constitutive exons with existed and new features based on the AdaBoost algorithm. Experimental results show that the accuracy is higher than current algorithms. The sensitivity is 81.92\% and the specificity is 74.06\%, namely that 81.92\% of cassette exons and 74.06\% of constitutive exons were correctly classified.",
keywords = "AdaBoost, Alternative splicing, Cassette exon, Maximum entropy",
author = "Liang Li and Qinke Peng and Adnan Shakoor and Tao Zhong and Shiquan Sun and Xiao Wang",
note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; 2014 IEEE International Conference on Information and Automation, ICIA 2014 ; Conference date: 28-07-2014 Through 30-07-2014",
year = "2014",
month = oct,
day = "21",
doi = "10.1109/ICInfA.2014.6932684",
language = "英语",
series = "2014 IEEE International Conference on Information and Automation, ICIA 2014",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "370--375",
booktitle = "2014 IEEE International Conference on Information and Automation, ICIA 2014",
}