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4th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 4)

  • F. Cardoso
  • , E. Senkus
  • , A. Costa
  • , E. Papadopoulos
  • , M. Aapro
  • , F. André
  • , N. Harbeck
  • , B. Aguilar Lopez
  • , C. H. Barrios
  • , J. Bergh
  • , L. Biganzoli
  • , C. B. Boers-Doets
  • , M. J. Cardoso
  • , L. A. Carey
  • , J. Cortés
  • , G. Curigliano
  • , V. Dié Ras
  • , N. S. El Saghir
  • , A. Eniu
  • , L. Fallowfield
  • P. A. Francis, K. Gelmon, S. R.D. Johnston, B. Kaufman, S. Koppikar, I. E. Krop, M. Mayer, G. Nakigudde, B. V. Offersen, S. Ohno, O. Pagani, S. Paluch-Shimon, F. Penault-Llorca, A. Prat, H. S. Rugo, G. W. Sledge, D. Spence, C. Thomssen, D. A. Vorobiof, B. Xu, L. Norton, E. P. Winer
  • Champalimaud Clinical Center
  • Medical University of Gdańsk
  • European School of Oncology
  • Europa Donna Cyprus
  • Clinique de Genolier
  • Institut Gustave Roussy
  • Ludwig Maximilian University of Munich
  • Direction Office
  • PURCS School of Medicine
  • Karolinska Institutet
  • Nuovo Ospedale di Prato – Istituto Toscano Tumori
  • CB Boers Organization
  • University of North Carolina at Chapel Hill
  • Hosp Valle De Hebron
  • University of Milan
  • Centre Georges-François Leclerc
  • American University of Beirut
  • Cancer Institute Prof Dr Ion Chiricuta
  • University of Sussex
  • Peter Maccallum Cancer Centre
  • Provincial Health Services Authority
  • Royal Marsden
  • Sheba Medical Center at Tel Hashomer
  • Bombay Hospital and Medical Research Centre
  • Dana-Farber Cancer Institute
  • AdvancedBC.org
  • UWOCASO (Uganda Women's Cancer Support Organization)
  • Aarhus University
  • Japanese Foundation for Cancer Research
  • University of Geneva
  • Shaare Zedek Medical Center
  • Centre Jean Perrin
  • Hospital Clinic
  • University of California at San Francisco
  • Stanford University
  • Breast Cancer Network Australia
  • Martin Luther University Halle-Wittenberg
  • Sandton Oncology Centre
  • Memorial Sloan-Kettering Cancer Center

Research output: Contribution to journalArticlepeer-review

1015 Scopus citations

Abstract

Advanced Breast Cancer (ABC) comprises both locally advanced breast cancer (LABC) and metastatic breast cancer (MBC) [1]. Although treatable, MBC remains virtually an incurable disease with a median overall survival (OS) of 3 years and a 5-year survival of only 25% [2, 3]. The MBC Decade Report [2] shows that progress has been slow in terms of improved outcomes, quality of life (QoL), awareness and information regarding ABC. More recently, some studies seem to indicate an improvement in OS, mostly due to advances in human epidermal growth factor receptor 2 (HER2)-positive ABC [4-6]. The better survival is seen in an environment with access to the best available care and particularly in de novo ABC, while recurrent ABC seems to become harder to manage [7, 8].

Original languageEnglish
Pages (from-to)1634-1657
Number of pages24
JournalAnnals of Oncology
Volume29
Issue number8
DOIs
StatePublished - Aug 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • ABC
  • Advanced
  • Breast cancer
  • ESO-ESMO
  • Guidelines
  • Metastatic

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