颈动脉体瘤切除术后颅神经损伤相关并发症危险因素分析

objective To analyze the risk factors for postoperative cranial nerve injury complications following carotid body tumor resection(CBTR). Methods The clinical data of 69 patients who had undergone CBTR in the First Affiliated Hospital of Xi'an Jiaotong University from January 2011 to December 2020 were retrospectively analyzed. Univariate analysis was performed on the related factors for postoperative cranial nerve injury complications. Unconditional binary multivariate logistic regression was used to analyze the correlation between the related factors with statistical significance in univariate analysis and the postoperative cranial nerve injury complications. Results Among 69 patients, there were 21 patients who developed postoperative cranial nerve injury, with incidence being 30.43%. Patients were divided into nerve injury group (observation group, n=21) and non-nerve injury group (control group, n=48) according to whether postoperative cranial nerve injury occurred. Univariate analysis showed aspartate transaminase (AST), alanine aminotransferase (ALT), Shamblin classification, onset time, external carotid artery ligation and neutrophil to lymphocyte ratio (NLR) were risk factors for postoperative cranial nerve injury following CBTR. Multivariate logistic regression analysis identified Shamblin classification and external carotid artery ligation as independent risk factors for postoperative cranial nerve injury complications. Conclusions Intraoperative external carotid artery ligation and Shamblin classification are independent risk factors for postoperative cranial nerve injury following CBTR.