Abstract
Idiopathic pulmonary fibrosis (IPF) is a common chronic interstitial fibrotic disease. During the fibrosis process, myofibroblasts are abnormally activated, collagen is deposited in large quantities and the biomechanical characteristics of lung tissue are significantly altered. In this paper, a systematic review about the changes in lung tissues, cellular biomechanical properties and biomechanical signals during the process of IPF was presented, and the in vitro reproduction of biomechanical features and therapeutic strategies for targeting biomechanics was summarized, so as to provide references for clinical prevention and treatment of IPF.
| Translated title of the contribution | Biomechanical Characteristics of Idiopathic Pulmonary Fibrosis |
|---|---|
| Original language | Chinese (Traditional) |
| Pages (from-to) | 195-201 |
| Number of pages | 7 |
| Journal | Yiyong Shengwu Lixue/Journal of Medical Biomechanics |
| Volume | 38 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 2023 |
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